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The selection of biotech stocks for investment is more difficult compared with the selection of other stocks and industries that possess historical data, since biotechnology is a recently new science. In the first edition of this book, we described the crucial parameters for the valuation of an early stage biotech company without a drug in the market. In this edition, we analyze novel financial models that can value stocks of biotech companies with products in the market or products under development (in pre-clinical and clinical studies). All of these parameters should be helpful to potential new investors when creating a stock portfolio that includes highly promising biotech companies. Our strategy of selecting highly promising stocks based on all parameters described in this book and of performing a basic financial modeling analysis with DFC and/or real options valuation models has proven very successful, as this strategy provides returns higher than 100% in most cases. In the first edition of this book, based on our strategy, we suggested that Juno Therapeutics and Kite Pharma were “hot” stocks. At that time, Kite’s stock was $50.19, while Juno’s stock was $54.21. Since then, Kite’s stock reached $179.79, with the company acquired by Gilead for $11.9 billion, while Juno’s stock reached $86.96, with the company acquired by Celgene for $9 billion. Furthermore, Moderna Therapeutics, a private company that we valued at $5.5 billion in 2016 based on our real options financial model, today has a $7.5 billion valuation. This newly revised and expanded version was written to help investors in the selection of biotech stocks based on different scientific and financial criteria.

This book describes seven areas in the field of biotechnology operations as practiced by biopharmaceutical firms and nonprofit institutions. Revisions focus upon changes that have occurred in several areas over the past six years, with emphasis on regulatory, biomanufacturing, clinical and technical information, along with processes and guidlines that have added to the discipline. Examples are increased for new technical fields such as cell and tissue engineering. Further, illustrations or figures are added to each chapter to emphasize particular points.

Without sufficient knowledge of classical and molecular genetics as well as of genetic engineering, it is not possible to fully unterstand biotechnological processes. Clear, concise and comprehensive, Volume 2 gives scientists all the information they need to carry out research and production in this field. In Part I of the book the classical genetic techniques relevant to biotechnology are presented. Part II highlights the recent advances in molecular genetics which have revolutionized our knowledge in the field. Part III deals with the genetic engineering of microorganisms, and Parts IV and V concentrate on plants and animals - multicellular organsims which require special genetic engineering techniques. In the final Part VI biosafety concepts in modern biotechnology are treated. Topics included are: Mutagenesis/ Genetic Exchange Processes/ Cell Fusion/ Gene Mapping/ Transposable Elements/ Gene Expression/ Synthesis of Oligonucleotides/ Polymerase Chain Reaction (PCR)/ Transposons/ Transformation Vectors/ Recombinant Proteins/ Gene Amplification/ Transgenic Plants and Animals/ Biosafety Concepts

At the dawn of the 21st century, biotechnology is emerging as a key enabling technology for sustainable environmental protection and stewardship. Biotechnology for the Environment: Wastewater Treatment and Modeling, Waste Gas Handling illustrates the current technological applications of microorganisms in wastewater treatment and in the control of waste gas emissions. In the first section of the book special emphasis is placed on the use of rigorous mathematical and conceptual models for an in-depth understanding of the complex biology and engineering aspects underlying the operation of modern wastewater treatment installations. The second part addresses waste gas biofiltration, an expanding biotechnological application of microbial metabolism for air quality assurance through processes ranging from the abatement of hazardous volatile pollutants to the elimination of nuisance odors. It will be a valuable reference source for environmental scientists, engineers and decision makers involved in the development, evaluation or implementation of biological treatment systems. For more information on Strategy and Fundamentals, see Focus on Biotechnology, Volume 3A, and for more information on Soil Remediation, see Focus on Biotechnology, Volume 3B.

This book describes seven areas in the field of biotechnology operations as practiced by biopharmaceutical firms and nonprofit institutions. Revisions focus upon changes that have occurred in several areas over the past six years, with emphasis on regulatory, biomanufacturing, clinical and technical information, along with processes and guidlines that have added to the discipline. Examples are increased for new technical fields such as cell and tissue engineering. Further, illustrations or figures are added to each chapter to emphasize particular points.

With Biotechnology and Society, Hallam Stevens offers an up-to-date primer to help us understand the interactions of biotechnology and society and the debates, controversies, fears, and hopes that have shaped how we think about bodies, organisms, and life in the twenty-first century. Stevens addresses such topics as genetically modified foods, cloning, and stem cells; genetic testing and the potential for discrimination; fears of (and, in some cases, hopes for) designer babies; personal genomics; biosecurity; and biotech art. Taken as a whole, the book presents a clear, authoritative picture of the relationship between biotechnology and society today, and how our conceptions (and misconceptions) of it could shape future developments. It is an essential volume for students and scholars working with biotechnology, while still being accessible to the general reader interested in the truth behind breathless media accounts about biotech’s promise and perils.

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This book provides detailed insights into the role of microorganisms and microbial products in biodeterioration, conservation and restoration of cultural heritage. Topics to be discussed are microbial colonization and their growth control on both artworks and aerosol of indoor environments such as libraries or museums, as well as human health hazard from exposure to microbial agents. In addition innovative biotechnological protocols and strategies for the removal of undesired layers on artwork surfaces are described in detail. Also the advances and perspectives in this emerging biotechnological field are discussed, supported by the latest original findings. 

Biotechnology for Beginners, Second Edition, presents the latest information and developments from the field of biotechnology―the applied science of using living organisms and their by-products for commercial development―which has grown and evolved to such an extent over the past few years that increasing numbers of professionals work in areas that are directly impacted by the science. For the first time, this book offers an exciting and colorful overview of biotechnology for professionals and students in a wide array of the life sciences, including genetics, immunology, biochemistry, agronomy, and animal science. This book also appeals to the lay reader without a scientific background who is interested in an entertaining and informative introduction to the key aspects of biotechnology. Authors Renneberg and Demain discuss the opportunities and risks of individual technologies and provide historical data in easy-to-reference boxes, highlighting key topics. The book covers all major aspects of the field, from food biotechnology to enzymes, genetic engineering, viruses, antibodies, and vaccines, to environmental biotechnology, transgenic animals, analytical biotechnology, and the human genome. This stimulating book is the most user-friendly source for a comprehensive overview of this complex field.Provides accessible content to the lay reader who does not have an extensive scientific backgroundIncludes all facets of biotechnology applicationsCovers articles from the most respected scientists, including Alan Guttmacher, Carl Djerassi, Frances S. Ligler, Jared Diamond, Susan Greenfield, and moreContains a summary, annotated references, links to useful web sites, and appealing review questions at the end of each chapterPresents more than 600 color figures and over 100 illustrationsWritten in an enthusiastic and engaging style unlike other existing theoretical and dry-style biotechnology books

At the dawn of the 21st century, biotechnology is emerging as a key enabling technology for sustainable environmental protection and stewardship. Biotechnology for the Environment: Wastewater Treatment and Modeling, Waste Gas Handling illustrates the current technological applications of microorganisms in wastewater treatment and in the control of waste gas emissions. In the first section of the book special emphasis is placed on the use of rigorous mathematical and conceptual models for an in-depth understanding of the complex biology and engineering aspects underlying the operation of modern wastewater treatment installations. The second part addresses waste gas biofiltration, an expanding biotechnological application of microbial metabolism for air quality assurance through processes ranging from the abatement of hazardous volatile pollutants to the elimination of nuisance odors. It will be a valuable reference source for environmental scientists, engineers and decision makers involved in the development, evaluation or implementation of biological treatment systems. For more information on Strategy and Fundamentals, see Focus on Biotechnology, Volume 3A, and for more information on Soil Remediation, see Focus on Biotechnology, Volume 3B.

An expert in the field presents a comprehensive and readable discussion of the moral, legal, psychological and sociological impact that modern forms of reproductive technology have on parenthood and the family. DeMarco looks beneath the surface of reproductive technology and exposes its deceptions, failures and dangers that threaten the very meaning of parenthood and family.

Some of humankind's greatest tools have been forged in the research laboratory. Who could argue that medical advances like antibiotics, blood transfusions, and pacemakers have not improved the quality of people's lives? But with each new technological breakthrough there comes an array of consequences, at once predicted and unpredictable, beneficial and hazardous. Outcry over recent developments in the reproductive and genetic sciences has revealed deep fissures in society's perception of biotechnical progress. Many are concerned that reckless technological development, driven by consumerist impulses and greedy entrepreneurialism, has the potential to radically shift the human condition―and not for the greater good. Biotechnology and the Human Good builds a case for a stewardship deeply rooted in Judeo-Christian theism to responsibly interpret and assess new technologies in a way that answers this concern. The authors jointly recognize humans not as autonomous beings but as ones accountable to each other, to the world they live in, and to God. They argue that to question and critique how fields like cybernetics, nanotechnology, and genetics might affect our future is not anti-science, anti-industry, or anti-progress, but rather a way to promote human flourishing, common sense, and good stewardship. A synthetic work drawing on the thought of a physician, ethicists, and a theologian, Biotechnology and the Human Good reminds us that although technology is a powerful and often awe-inspiring tool, it is what lies in the heart and soul of who wields this tool that truly makes the difference in our world.

Biotechnology and Culture: Bodies, Anxieties, Ethics 0.96

Succeed in this course and your future career with BIOTECHNOLOGY with InfoTrac! Using case studies and examples, this biology text provides you with the tools you need to understand the methods, implications, and debate surrounding the use of biotechnological products now and in the future. Coverage includes the human genome and other genomes, animal cloning, pharmacogenomics, plant bioreactors, RNA interference, microarray technology, microbial surface display, and biotechnology regulation and patent information. Mastering difficult material is made easy with the book-specific website that provides you with learning aids such as flashcards, exercises, and tutorial quizzes.

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Biotechnology and Biopharmaceuticals: Transforming Proteins and Genes into Drugs defines biotechnology from the perspective of pharmaceuticals. The first section focuses on the process of transforming a biologic macromolecule into a therapeutic agent, while the second section provides a brief overview of each class of macromolecule with respect to physiological role and clinical application. Additional detail is also provided in the second section for each FDA approved, recombinantly derived biopharmaceutical for each category of macromolecule. The final section looks to the future and the new advances that will enhance our ability to develop new macromolecules into effective biopharmaceuticals. This last section discusses various drug delivery strategies while also describing gene and cell therapy strategies.

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