12 products were found matching your search for Conformational in 1 shops:

Contains 15 chapters conceptually arranged into four groups—introductory material for theoretical description of chain molecules and experimental observations frequently addressed by rotational isomeric state techniques; development of the rotational isomeric state model from simple alkanes; expansion on the scope of polymer types that can be treated with this model; and extension regarding the scope of types of conformation-dependent physical properties that can be so treated. Includes scores of problems plus a FORTRAN program that performs calculations for the most important property—the characteristic ratio.

A unique guide to variable temperature CD spectroscopy and its application in organic chemistry This timely, original, thought-provoking work looks at organic stereochemistry from the perspective of circular dichroism (CD), using variable temperature CD spectroscopy to determine the conformation or absolute configuration of chiral molecules. With an emphasis on the analysis of optically active ketones and the carbonyl chromophore, the authors demonstrate the advantages of this highly sensitive spectroscopic tool for obtaining stereochemical information in diverse areas of organic chemistry, biochemistry, and medicinal/pharmaceutical chemistry. They combine detailed examples of stereochemical analysis with clear, thorough presentations, correlating chiroptical data with molecular mechanics calculations as well as data from NMR spectroscopy and other spectroscopic techniques. In addition, they provide a systematic survey of the professional literature, featuring an extraordinary collection of original CD spectra run at varying temperatures. Coverage includes: * Chiroptical measurements: CD and ORD (Optical Rotatory Dispersion) * Conformational analysis of compounds ranging from simple cyclic ketones to polycyclics * Conjugated and homoconjugated systems * Stereochemistry of the carbon-carbon double bond * Stereochemistry from exciton coupling of two or more chromophores * An interesting historical account of the development of stereochemical concepts

A unique guide to variable temperature CD spectroscopy and its application in organic chemistry This timely, original, thought-provoking work looks at organic stereochemistry from the perspective of circular dichroism (CD), using variable temperature CD spectroscopy to determine the conformation or absolute configuration of chiral molecules. With an emphasis on the analysis of optically active ketones and the carbonyl chromophore, the authors demonstrate the advantages of this highly sensitive spectroscopic tool for obtaining stereochemical information in diverse areas of organic chemistry, biochemistry, and medicinal/pharmaceutical chemistry. They combine detailed examples of stereochemical analysis with clear, thorough presentations, correlating chiroptical data with molecular mechanics calculations as well as data from NMR spectroscopy and other spectroscopic techniques. In addition, they provide a systematic survey of the professional literature, featuring an extraordinary collection of original CD spectra run at varying temperatures. Coverage includes: * Chiroptical measurements: CD and ORD (Optical Rotatory Dispersion) * Conformational analysis of compounds ranging from simple cyclic ketones to polycyclics * Conjugated and homoconjugated systems * Stereochemistry of the carbon-carbon double bond * Stereochemistry from exciton coupling of two or more chromophores * An interesting historical account of the development of stereochemical concepts

This book bridges the gap between sophomore and advanced / graduate level organic chemistry courses, providing students with a necessary background to begin research in either an industry or academic environment. · Covers key concepts that include retrosynthesis, conformational analysis, and functional group transformations as well as presents the latest developments in organometallic chemistry and C–C bond formation· Uses a concise and easy-to-read style, with many illustrated examples· Updates material, examples, and references from the first edition· Adds coverage of organocatalysts and organometallic reagents

Dr. Eliel gained fame for his forty years of research in stereochemistry and conformational analysis. He tells of a fascinating life beginning with his flight from Nazi Germany through his worldwide studies and work at Notre Dame and the University of North Carolina. Included in this volume are many photographs and discussion of his scientific studies.

Recognizing the Horse in Pain is back in a second edition! Now in a fully expanded, updated, and revised edition, this favorite among equestrians is better than ever with new illustrations and images, new topics, and a massive overhaul. Learn about conformational, behavioral, and training issues related to equine pain, and understand both Western and Eastern approaches to diagnostics and treatment. Learn about the anatomy of saddle-fit and how to check your own saddle, common fitting issues related to conformation and injuries related to poor fit. See basic stretches you can do with your horse, and understand the importance of getting your horse engaged in the core and lifted in its back. From anatomy to compounded medications, saddle-pads to acupuncture, this book contains all the must-have information, with references and research, for the horseman or horsewoman who wants to understand the language of the horse and put their horses first!

This book bridges the gap between sophomore and advanced / graduate level organic chemistry courses, providing students with a necessary background to begin research in either an industry or academic environment. · Covers key concepts that include retrosynthesis, conformational analysis, and functional group transformations as well as presents the latest developments in organometallic chemistry and C–C bond formation· Uses a concise and easy-to-read style, with many illustrated examples· Updates material, examples, and references from the first edition· Adds coverage of organocatalysts and organometallic reagents

Adopting a bio-organic emphasis, this textbook introduces functional groups early in the text, providing an overview of and preparation for subsequent discussions. This edition includes increased coverage of Carbon 13 spectra; an expanded treatment of conformational effects of molecules, with two sections covering basic geometries of molecules and an in-depth overview of the subject; plus new material on transition metal chemistry and carbohydrate metabolism. Worked examples have been added to chapters on synthesis, and end-of-chapter problems have been expanded by more than 200. The text also includes graphics illustrating conformational effects and general stereochemical properties of organic substances.

Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.

This volume is an autobiography of Vladimir Prelog, eminent chemist and 1975 Nobel Laureate. After a long and rewarding career as lecturer and researcher, Prelog remains active in Zurich academic life. Known for his charm and wit, he relates his life and work in natural products chemistry and in conformational analysis and stereochemistry. Together with Cahn and Ingold, Prelog developed the R,S nomenclature for organic configuration.

Recognizing the Horse in Pain is back in a second edition! Now in a fully expanded, updated, and revised edition, this favorite among equestrians is better than ever with new illustrations and images, new topics, and a massive overhaul. Learn about conformational, behavioral, and training issues related to equine pain, and understand both Western and Eastern approaches to diagnostics and treatment. Learn about the anatomy of saddle-fit and how to check your own saddle, common fitting issues related to conformation and injuries related to poor fit. See basic stretches you can do with your horse, and understand the importance of getting your horse engaged in the core and lifted in its back. From anatomy to compounded medications, saddle-pads to acupuncture, this book contains all the must-have information, with references and research, for the horseman or horsewoman who wants to understand the language of the horse and put their horses first!

The focus of this book is on the molecular basis for liquid crystallinity in polymers, including lyotropic, thermotropic, mainchain, sidechain systems and mixtures. An entire section is devoted to conformational aspects of polymeric mesogens which is followed by a section describing current molecular theories. Another section on experimental behaviour analyzes the performance of these theories, pointing out areas where further investigation is needed. A final section deals with elastic and viscous properties, with defects and textures and with rheology of LCP. "Liquid crystallinity in polymers" is written by recognized specialists whose various chapters together reach a consensus on the current status of our understanding of LCP behaviour. Specialists, chemists, physicists and biochemists entering the field will find it useful as will material researchers closer to application.