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The main argument of this book is that cell signalling via nerves, hormones, local mediators and growth factors are not distinct phenomena, but branches of one general mechanism and should therefore be studied in an integrated manner. This volume is designed to act as a bridge between general texts and is aimed at biologists coming to the topic from a variety of backgrounds. The first two chapters introduce the general concepts of intracellular signalling and also cover the topic of direct cell-to-cell communication by cytoplasmic bridges (gap junctions). The remaining chapters cover the first and second messengers, starting with their structure, synthesis and release, progressing to the target cell and then working from the membrane inwards towards the nucleus. There is also a section on the mechanism of nervous conduction and the regulation of the ionic balace of cells. The final chapters discuss the regulation of cell growth and division and the special case of messengers acting via nuclear receptors.

This two-volume treatise, the collected effort of more than 50 authors, represents the first comprehensive survey of the chemistry and biology of the set of molecules known as peptide growth factors. Although there have been many symposia on this topic, and numerous publications of reviews dealing with selected subsets of growth factors, the entire field has never been covered in a single treatise. It is essential to do this at the present time, as the number of journal articles on peptide growth factors now makes it almost impossible for anyone person to stay informed on this subject by reading the primary literature. At the same time it is becoming increasingly apparent that these substances are of universal importance in biology and medicine and that the original classification of these molecules, based on the laboratory setting of their discovery, as "growth factors," "lymphokines," "cytokines," or "colony­ stimulating factors," was quite artifactual; they are in fact the basis of a com­ mon language for intercellular communication. As a set they affect essentially every cell in the body, and in this regard they provide the basis to develop a unified science of cell biology, germane to all of biomedical research. This treatise is divided into four main sections. After three introductory chapters, its principal focus is the detailed description of each of the major peptide growth factors in 26 individual chapters.

This is the most comprehensive, yet practical guide to using growth hormone therapy. Learn how this remarkable hormone can help you to look younger and feel younger while reversing biological aging by 20 years or more. See the amazing results of human studies that demonstrate the effeciveness and safety of HGH therapy. Learn about natural secretagogues that have been shown to restore youthful levels of HGH safely and naturally. Discover the most effective GH enhancing dietary and exercise recommendations.

This book describes and summarizes the radiation responses of both normal and neoplastic tissues with a focus on rational strategies for the modification of these responses. Emerging data from molecular oncology and radiobiology that form the basis for a better understanding of radiation-induced reactions and key features of malignant growth are reviewed in depth. The book covers not only general principles of radiation-induced reactions but also a large number of preclinical and clinical data that will guide the reader through this complex and dynamic field and will provide valuable information for the development of further research projects. Many of the data reviewed in this book form a sound basis for further improvement of state-of-the art radiation therapy by integrating biological information into the process of treatment planning and delivery.

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WHAT IT IS The Beard is a vegan beard growth serum with KGF keratinocyte growth factor. It makes your beard more soft and touchable and rejuvenates your skin. Replenish skin's moisture with sea kelp ferment and other soothing ingredients. Made in USA. TWO-PIECE SET INCLUDED: Beard growth serum, 2 oz. x 2 HOW TO USE IT Dispense two-three pumps into palm and massage thoroughly onto the skin. Work excess amount throughout the beard. Saks Off 5th. Tombstone for Men.

A report on the effects of starvation on physical growth and social and national behavior is based on first-hand experience of famine and misery in Russian provinces during the 1920's

A revolution in usability is fueling the continued growth of the computer industry. Graphical user interfaces and improved input/output devices have made computing power more accessible to wider variety of people. Despite these advances, there is still a need to raise awareness of the human factors in user interface design, and this book is designed to meet this need.

If you have ever dreamed of developing a business that achieves extraordinary results, The Synergy Factor will show you how. Learn how harnessing the power of people and processes can create unlimited profits and growth. You’ll be guided step-by-step to achieving peak performance, giving you the knowledge to grow to your next level – including total freedom. This powerful book is written by Gary Holt, CEO of Holt Marketing & Management. Gary has spent over 20 years providing business owners, managers and sales people the help they need to build successful careers and businesses.

The field of neurotrophic factors has witnessed exp- sive growth in the past decade. As is usual in scientific in- vation, this progress has been closely associated with methodological advances. The introduction of molecular b- logical techniques into the neurotrophic factor field led to the discovery of new families of neurotrophic growth f- tors and their receptors. Production of growth factors by recombinant technology played a crucial part. The example of nerve growth factor, the paradigmatic neurotrophic factor, illustrates this point. A decade ago investigators were forced to purify small quantities of this protein from murine salivary glands, but much larger qu- tities of recombinant nerve growth factor are now available for experimentation as well as clinical development. A decade ago there was a controversy about the existence of nerve growth factor in the brain and the immunoassays used for its measurement, but current publications report the precise localization of gene expression for nerve growth factor and its receptor in the brain. Neurotrophic Factors aims at presenting the techniques that have been crucial to the realization of these rapid advances and thus have helped propel the neurotrophic factors field to its current status of high visibility. These techniques range from molecular biological methods used for cloning and production, to cell culture methods for assessing biological activities, to animal models of nervous system injury (nec- sary for the development of therapeutic agents from neurotrophic factors).

The author presents a theory that major genes controlling the growth of human intelligence, both left- and right-brain attributes, are on the X-chromosome. The more significant of the implications of such X-linkage include:^L^L ^DBL Males tend to be more variable in intelligence. It is well known that males are far more likely to have intellectual deficits, including mental subnormality, learning disorders, and behavior problems. This book also presents evidence that males are more likely to be exceptionally high in cognitive abilities (other than memory), and in such areas as advanced mathematics, spatial perception, and creative music.^L ^L ^DBL Partial or total reversions to the aboriginal level of intelligence can account for virtually all cases of non-specific mental subnormality. These conditions are now identified by such terms as Renpenning syndrome, Martin-Bell syndrome, Fragile-X syndrome, and cultural-familial mental retardation. Because of the probability of offsetting genes, females are less likely to be severely affected by these conditions.^DBL Since the X-linked genes control a pattern of growth, boys are more variable in the age of readiness for the skills required for progress in school. Some are precocious, but many are delayed, and not ready for the three R's at the traditional age of 6. This is the basis for almost all cases of learning disability.^L^L ^DBL Being on the X-chromosome, these genes, favorable or unfavorable, are not passed on from father to son, although they are passed on from father to daughter. This invalidates earlier studies of parent-child transmission of IQ, which have included father-son correlations. In effect, earlier studies have come up with estimates of the heritability of intelligence that are too low.

This book brings together a number of previously published articles by Stanley L. Engerman and Kenneth L. Sokoloff. Its essays deal with differences in the rates of economic growth in Latin American and mainland North America, specifically the United States and Canada. It demonstrates how relative differences in growth over time are related to differences in the institutions that developed in different economies. This variation is driven by differences in major institutions - suffrage, education, tax policy, land and immigration policy, and banking and financial organizations. These factors, in turn, are all related to differences in endowments, climate, and natural resources. Providing a comprehensive treatment of its topic, the essays have been revised to reflect new developments and research.

Garrett Hardin, one of our leading thinkers on problems of human overpopulation, here assails the recklessness and basic ecological ignorance of economists and others who champion the idea of unbounded growth. Hardin delivers an uncompromising critique of mainstream economic thinking. Science has long understood the limits of our environment, he notes, and yet economists consistently turn a blind eye to one feature we share with all of our planet's inhabitants--the potential for irreversible environmental damage through overcrowding. And as humankind draws ever closer to its goal of conquering our final natural enemy--disease--the fallacy of sustainable unchecked population growth becomes more and more dangerous. Moreover, Hardin argues, rampant growth will soon force us to face many issues that we will find quite unpalatable--most notably, that since volunteer population control will not work, we will have to turn to "democratic coercion" or "mutual coercion, mutually agreed upon" to limit growth, a policy that directly threatens long cherished personal rights. Challenging an array of powerful taboos, Hardin takes aim at sacred cows on both sides of the political fence--affirmative action, multiculturalism, current immigration policies, and the greed and excess of big business and "growth intoxicated industrialists." Hardin's forceful and cogent argument for the union of ecology and economics is a must for anyone concerned with the goal of a bountiful, yet sustainable world. Sure to spark controversy, this book underscores the urgency of our situation and reveals practical steps we must take to ensure the long term survival of humankind.

This book presents a model for examining problems of institutional change and applies it to American economic development in the nineteenth and twentieth centuries. The authors develop their model of institutional change. They argue that if external economic factors make an increase in income possible but not attainable within the existing institutional structure, new organizations must be developed to achieve the potential in income. Their model is designed to explain the type and timing of these necessary changes in institutional organization. Individual, voluntary cooperative, and governmental arrangements are included in the discussion, although the latter differs considerably from the first two.

Modern Asian economic history has often been written in terms of Western impact and Asia's response to it. This volume argues that the growth of intra-regional trade, migration, and capital and money flows was a crucial factor that determined the course of East Asian economic development.

Examines the factors which limit human economic and population growth and outlines the steps necessary for achieving a balance between population and production. Bibliogs