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The enormous recent success of molecular developmental biology has yielded a vast amount of new information on the details of development. So much so that we risk losing sight of the underlying principles that apply to all development. To cut through this thicket, John Tyler Bonner ponders a moment in evolution when development was at its most basic--the moment when signaling between cells began. Although multicellularity arose numerous times, most of those events happened many millions of years ago. Many of the details of development that we see today, even in simple organisms, accrued over a long evolutionary timeline, and the initial events are obscured. The relatively uncomplicated and easy-to-grow cellular slime molds offer a unique opportunity to analyze development at a primitive stage and perhaps gain insight into how early multicellular development might have started. Through slime molds, Bonner seeks a picture of the first elements of communication between cells. He asks what we have learned by looking at their developmental biology, including recent advances in our molecular understanding of the process. He then asks what is the most elementary way that polarity and pattern formation can be achieved. To find the answer, he uses models, including mathematical ones, to generate insights into how cell-to-cell cooperation might have originated. Students and scholars in the blossoming field of the evolution of development, as well as evolutionary biologists generally, will be interested in what Bonner has to say about the origins of multicellular development--and thus of the astounding biological complexity we now observe--and how best to study it.

Understanding how a multicellular animal develops from a single cell (the fertilized egg) poses one of the greatest challenges in biology today. Development from egg to adult involves the sequential expression of virtually the whole of an organism's genetic instructions both in the mother as she lays down developmental cues in the egg, and in the embryo itself. Most of our present information on the role of genes in development comes from the invertebrate fruit fly, Drosophila. The two authors of this text (amongst the foremost authorities in the world) follow the developmental process from fertilization through the primitive structural development of the body plan of the fly after cleavage into the differentiation of the variety of tissues, organs and body parts that together define the fly. The developmental processes are fully explained throughout the text in the modern language of molecular biology and genetics. This text represents the vital synthesis of the subject that many have been waiting for and it will enable many specific courses in developmental biology and molecular genetics to focus on it. It will appeali to 2nd and 3rd year students in these disciplines as well as in biochemistry, neurobiology and zoology. It will also have widespread appeal among researchers. Authored by one of the foremost authorities in the world. A unique synthesis of the developmental cycle of Drosophila - our major source of information on the role of genes in development. Designed to provide the basis of new courses in developmental biology and molecular genetics at senior undergraduate level. A lucid explanation in the modern language of the science.

The fungi realm has been called the "hidden kingdom," a mysterious world populated by microscopic spores, gigantic mushrooms and toadstools, and a host of other multicellular organisms ranging widely in color, size, and shape. The Kingdom of Fungi provides an intimate look at the world's astonishing variety of fungi species, from cup fungi and lichens to truffles and tooth fungi, clubs and corals, and jelly fungi and puffballs. This beautifully illustrated book features more than 800 stunning color photographs as well as a concise text that describes the biology and ecology of fungi, fungal morphology, where fungi grow, and human interactions with and uses of fungi. The Kingdom of Fungi is a feast for the senses, and the ideal reference for naturalists, researchers, and anyone interested in fungi. Reveals fungal life as never seen before Features more than 800 stunning color photos Describes fungal biology, morphology, distribution, and uses A must-have reference book for naturalists and researchers

For centuries scientists have tried to understand the growth and development of multicellular organisms. More recently, with the help of mathematical models and computerized simulations, they have discovered algorithmic patterns and models that seem to describe the dynamic processes in which organisms grow, reproduce, and respond to external factors. In this fascinating and beautifully illustrated book, Hans Meinhardt explains and illustrates these structural growth patterns in the case of sea shells. The book delightfully conveys the intuitive appeal and the "touch of magic" in this research. A diskette packaged with the book contains a program that allows the reader to run the simulations on a PC. New patterns can be generated interactively to provide an insight into the process of biological pattern formation.

Twenty-six essays probe the phenomena of the universe that have shaped and will shape the future of man from the development of multicellular life to twenty possible ways the world could end

The epic story of the beginning of life on Earth from the much loved and respected naturalist, writer and broadcaster, Sir David Attenborough.Spanning billions of years, First Life reveals the extraordinary story of the evolution of the first life on Earth and how it then evolved into multicellular life, the first plant, the first animal, the first predator, the first to live on land: key moments in the development of the huge diversity of life that has lived on planet Earth. First Life travels the world, from Canada to Australia, Morocco to Scotland, to unearth the secrets hidden in prehistoric fossils and meet the palaeontologists who have harnessed new techniques to enhance greatly our understanding of the origins of life.With an introduction by David Attenborough, and insights captured during the making of the television series, this book is a journey of discovery, showing us what these early animals would have looked like and how they would have lived, bringing them to life with the help of modern computer technology. First Life shows us how evolutionary features of the first creatures have been passed down to modern animals, including humans, giving us amazing insight into the remarkable evolutionary journey that has brought us here today.

he greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory of how embryos build themselves, and combines simple physics with the most recent biochemical and genetic breakthroughs, based on the authors' prediction and then discovery of differentiation waves. They explain their ideas in a form accessible to the lay person and a broad spectrum of scientists and engineers. The diverse subjects of development, genetics and evolution, and their physics, are brought together to explain this major, previously unanswered scientific question of our time.As a follow up on The Hierarchical Genome, this book is a shorter but conceptually expanded work for the reader who is interested in science. It is useful as a starting point for the curious layman or the scientist or professional encountering the problem of embryogenesis without the formal biology background. There is also material useful for the seasoned biologist caught up in the new rush of information about the role of mechanics in developmental biology and cellular level mechanics in medicine.

he greatest mystery of life is how a single fertilized egg develops into a fully functioning, sometimes conscious multicellular organism. Embryogenesis Explained offers a new theory of how embryos build themselves, and combines simple physics with the most recent biochemical and genetic breakthroughs, based on the authors' prediction and then discovery of differentiation waves. They explain their ideas in a form accessible to the lay person and a broad spectrum of scientists and engineers. The diverse subjects of development, genetics and evolution, and their physics, are brought together to explain this major, previously unanswered scientific question of our time.As a follow up on The Hierarchical Genome, this book is a shorter but conceptually expanded work for the reader who is interested in science. It is useful as a starting point for the curious layman or the scientist or professional encountering the problem of embryogenesis without the formal biology background. There is also material useful for the seasoned biologist caught up in the new rush of information about the role of mechanics in developmental biology and cellular level mechanics in medicine.

Examines the building block of organic matter, from its first appearance three million years ago in the ancient Earth's oceans to the rise of multicellular organisms and the technologies of the late twentieth century including cloning and stem cell therapy.

For centuries scientists have tried to understand the growth and development of multicellular organisms. More recently, with the help of mathematical models and computerized simulations, they have discovered algorithmic patterns and models that seem to describe the dynamic processes in which organisms grow, reproduce, and respond to external factors. In this fascinating and beautifully illustrated book, Hans Meinhardt explains and illustrates these structural growth patterns in the case of sea shells. The book delightfully conveys the intuitive appeal and the "touch of magic" in this research. A diskette packaged with the book contains a program that allows the reader to run the simulations on a PC. New patterns can be generated interactively to provide an insight into the process of biological pattern formation.

This truly comparative text takes a fundamental, biophysical approach toward animal physiology. Students majoring in zoology, biology, or premedicine will study animals ranging from simple invertebrates and protozoans to complex multicellular invertebrates and vertebrates. Emphasis on evolution shows the progressive changes, modifications, and developments of physiological systems from simple to complex animals. Comparisons show the similarities and differences in how animals function, but stress fundamentally similar adaptations in very different animals.

This text describes the evidence for how life moved from sea to land, beginning more than 400 million years ago, employing the concept of Hypersea which is the idea that the barren land surfaces of the Earth could only have been colonized by multicellular organisms working in concert.

Sponges are animals of the phylum Porifera. They are multicellular organisms which have bodies full of pores and channels allowing water to circulate through them, consisting of jelly-like mesohyl sandwiched between two thin layers of cells.