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Neuroprotection is becoming an increasingly recognized and important part of critical care and perioperative medicine. As human beings survive increasingly severe life-threatening injuries and complex surgical interventions, it has become clear that neurologic injury and dysfunction is a primary driver of long-term outcome and disability. Neuroprotection is currently under-recognized as the primary objective in promoting recovery from life-threatening injuries, illnesses, and procedures. To address this knowledge gap, Neuroprotection in Critical Care and Perioperative Medicine provides a concise review of the current state of the art of clinical care and research. Within the context of critical care, the specific topics covered will include the primary forms of brain injury on which neuroprotection research and intervention has traditionally focused, such as traumatic brain injury, cardiac arrest, acute ischemic stroke, and intracranial hemorrhage, as well as CNS injuries related to sepsis and acute respiratory distress syndrome, mechanical circulatory support, and premature birth. Within the context of perioperative care, the specific topics covered will include anesthetic and perioperative strategies to reduce brain injury from cardiac surgery, aortic surgery and endovascular repair, carotid endarterectomy, vascular and endovascular neurosurgery, and other major surgical procedures.

Neuroprotection is becoming an increasingly recognized and important part of critical care and perioperative medicine. As human beings survive increasingly severe life-threatening injuries and complex surgical interventions, it has become clear that neurologic injury and dysfunction is a primary driver of long-term outcome and disability. Neuroprotection is currently under-recognized as the primary objective in promoting recovery from life-threatening injuries, illnesses, and procedures. To address this knowledge gap, Neuroprotection in Critical Care and Perioperative Medicine provides a concise review of the current state of the art of clinical care and research. Within the context of critical care, the specific topics covered will include the primary forms of brain injury on which neuroprotection research and intervention has traditionally focused, such as traumatic brain injury, cardiac arrest, acute ischemic stroke, and intracranial hemorrhage, as well as CNS injuries related to sepsis and acute respiratory distress syndrome, mechanical circulatory support, and premature birth. Within the context of perioperative care, the specific topics covered will include anesthetic and perioperative strategies to reduce brain injury from cardiac surgery, aortic surgery and endovascular repair, carotid endarterectomy, vascular and endovascular neurosurgery, and other major surgical procedures.

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Melanin is a biological molecule associated with pigmentation in humans and animals. However, melanin has been observed to have other functions such as neuroprotection and energy production. In Melanin, the Master Molecule, researchers summarize several decades worth of knowledge on melanin and its physicochemical properties. Nine chapters explain the intrinsic biochemistry of melanin, comparisons with conventional energy producing and respiratory biomolecules, the property of melanin to transform light energy into chemical energy through the dissociation of the water molecule, and the theories of melanin based energy production in the nervous system, the cell nucleus, muscles and the eye, and the role the role of melanin in the context of ageing. The authors also delve into the possibility of melanin being the key molecule needed to spark life since its water dissociating property through the absorption of light energy emulates the role of chlorophyll, but unlike the latter, it is not limited to the plant cell environment. Hence, melanin is referred to as the master molecule which can provide a missing link to the biochemical processes behind the origin of life. Melanin, the Master Molecule is an exciting reference for biochemists and laymen interested in the science of melanin and a new perspective on the origin of life as we know it.

Melanin is a biological molecule associated with pigmentation in humans and animals. However, melanin has been observed to have other functions such as neuroprotection and energy production. In Melanin, the Master Molecule, researchers summarize several decades worth of knowledge on melanin and its physicochemical properties. Nine chapters explain the intrinsic biochemistry of melanin, comparisons with conventional energy producing and respiratory biomolecules, the property of melanin to transform light energy into chemical energy through the dissociation of the water molecule, and the theories of melanin based energy production in the nervous system, the cell nucleus, muscles and the eye, and the role the role of melanin in the context of ageing. The authors also delve into the possibility of melanin being the key molecule needed to spark life since its water dissociating property through the absorption of light energy emulates the role of chlorophyll, but unlike the latter, it is not limited to the plant cell environment. Hence, melanin is referred to as the master molecule which can provide a missing link to the biochemical processes behind the origin of life. Melanin, the Master Molecule is an exciting reference for biochemists and laymen interested in the science of melanin and a new perspective on the origin of life as we know it.