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Hardcover with dust jacket in Good condition. Clean pages. Good binding. Carefully packaged to avoid damage in shipping.

The study of interactions between genes and environmental exposures has expanded considerably in recent years. Highly penetrant genes that are involved in familial cancer have been identified, but are likely to account for a relatively small proportion of total cancers. Other predisposinggenes have low penetrance, resulting in a moderate increase in the risk of specific cancers, but are widespread in the general population. This is the case for so-called metabolic polymorphisms. Scientific interest in metabolic polymorphisms is based on the possibility of identifying subgroups ofthe population which are at elevated risk of developing environmentally-induced cancer. However, such studies raise a series of problems that are methodological - related to the study design and analysis - and ethical - related to the practical use that can be made of genetic information. Thisvolume deals thoroughly with such problems.

This is the second part of the three-volume set Peonies of the World, a comprehensive taxonomic revision of the genus Paeonia. Based on Hong De-Yuan’s extensive field work and supported by the National Geographic Society, this book contains 356 color photographs taken from natural sites covering all peony species and subspecies, accompanied by descriptions of morphology and distribution. Peonies of the World will be the definitive guide to the species for growers, gardeners, and collectors.

This is the second part of the three-volume set Peonies of the World, a comprehensive taxonomic revision of the genus Paeonia. Based on Hong De-Yuan’s extensive field work and supported by the National Geographic Society, this book contains 356 color photographs taken from natural sites covering all peony species and subspecies, accompanied by descriptions of morphology and distribution. Peonies of the World will be the definitive guide to the species for growers, gardeners, and collectors.

Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.

*** Can you invest two days advancing your career? In eight sessions you apply the power of C++ to a net-centric UAV simulation. As you study the more than 250 PowerPoint slides you use polymorphism, inheritance, and encapsulation to create a multi-object simulation on your Windows based computer, consisting of UAVs, targets, and satellites. *** This workshop is the condensed version of a course I taught at the University of Florida. Like the students, you should come with a first knowledge of C++ and a general understanding of flight dynamics. Step-by-step I combine C++ constructs with increasingly more complex aerospace features. You will be given access to eight simulations that replicate this build-up, culminating in the final multi-object CRUISE simulation. *** The C++ simulation framework is based on CADAC++. By working through this course you also acquire the fundamentals for my other simulations of missiles, aircraft, boosters, and hypersonic vehicles. So take the challenge and get started! **** Other publications by the author at Amazon: ** Modeling and Simulation of Aerospace Vehicle Dynamics ** Building Aerospace Simulations in C++ ** Fundamentals of Six DoF Aerospace Simulations and Analysis in C++ ** Advanced Six DoF Aerospace Simulations and Analysis in C++ ** Modeling INS/GPS/Star-Tracker in 6 DoF ** Introduction to Tensor Flight Dynamics ** Flight Dynamics Workshop in Three Days.

Volume 2 This second book of the Learning C# series continues where the first book left off, focusing on intermediate C# programming concepts. The topics you will study in this volume include: · Advanced object-oriented programming techniques · Composition · Interfaces · Inheritance · Polymorphism · Operator overloading · Extension methods · Anonymous types · Custom type formatting · Creational design patterns · Assemblies and libraries · File I/O · Program configurations · Serialization · Software reliability This book will reinforce your programming skills and provide key insights into the world of object-oriented programming. Additionally, the topics learned in this volume will prepare you for advanced C# techniques such as: multi-threaded programming, generics, reflection and using the DLR.

Epigenetics is emerging as an important factor in risk of diseases of global importance including obesity, cardiovascular disease and cancer. Unlike gene polymorphisms which have been the focus of understanding the role of inherited disease susceptibility for some time, epigenetic can be modified by environmental factors, in particular nutrition. Thus research into the role of epigenetics in disease has substantial potential for explaining the impact of the environmental factors such as diet on disease risk. Since epigenetic processes can be modified by nutrition, it may be possible to modify inappropriate epigenetic marks by nutritional interventions to reduce disease risk. This book will explore current understanding of the interaction between nutrition, epigenetics and disease risk, will place this knowledge in the context of global health and discuss the ethical implications of this research.

If you're a programmer using C++, Smalltalk, or Eiffel, or if you're about to migrate to object orientation for the first time, you need to know the most important principles of object-oriented design. For example: In a reliable design, why must a variable's cone of polymorphism lie within that of a method. Is connascence good or bad? How could the inherited methods of a superclass violate the invariant of a subclass -- and how can this be prevented? Page-Jones answers these questions and more, with characteristic clarity, demystifying the fundamentals of object orientation in a language-independent way. He provides a comprehensive notation for object-oriented design that allows you to depict the design for a whole system or to jot down back-of-the-envelope ideas.         features 150+ diagrams and exercises   Topics Include * Encapsulation * Information Hiding * State Retention * Object Identity * Synchronous and Asynchronous Messages * Classes and Subclasses * Inheritance * Polymorphism * Genericity * Reusability * The Object-Communication Diagram * States and Transitions * Connascence * Class Domains * Encumbrance * State Space and Behavior * Class Cohesion * Guide to Object-Oriented Terminology * Object-Orientation in a Historical Context From the Foreword ". . . vintage Page-Jones. . . . Meilir is a gifted teacher. . . . a relentlessly pragmatic focus based on real-world experience . . . compact examples to guide the developer, whether novice or old hand, toward better object-oriented software solutions. . . . Who could ask for more?"               -- Larry L. Constantine

If you're a programmer using C++, Smalltalk, or Eiffel, or if you're about to migrate to object orientation for the first time, you need to know the most important principles of object-oriented design. For example: In a reliable design, why must a variable's cone of polymorphism lie within that of a method. Is connascence good or bad? How could the inherited methods of a superclass violate the invariant of a subclass -- and how can this be prevented? Page-Jones answers these questions and more, with characteristic clarity, demystifying the fundamentals of object orientation in a language-independent way. He provides a comprehensive notation for object-oriented design that allows you to depict the design for a whole system or to jot down back-of-the-envelope ideas.         features 150+ diagrams and exercises   Topics Include * Encapsulation * Information Hiding * State Retention * Object Identity * Synchronous and Asynchronous Messages * Classes and Subclasses * Inheritance * Polymorphism * Genericity * Reusability * The Object-Communication Diagram * States and Transitions * Connascence * Class Domains * Encumbrance * State Space and Behavior * Class Cohesion * Guide to Object-Oriented Terminology * Object-Orientation in a Historical Context From the Foreword ". . . vintage Page-Jones. . . . Meilir is a gifted teacher. . . . a relentlessly pragmatic focus based on real-world experience . . . compact examples to guide the developer, whether novice or old hand, toward better object-oriented software solutions. . . . Who could ask for more?"               -- Larry L. Constantine

Features *Teaches students why the Java language works the way it does, as opposed to simply how it works *NEW! Chapter on Network Programming *NEW! Chapter on Java 2 - the most recent version of Java *NEW! Material on pure polymorphism *NEW! Appendices on Java Operators, Java Escape Characters, Java API, and Java Syntax

Volume 2 This second book of the Learning C# series continues where the first book left off, focusing on intermediate C# programming concepts. The topics you will study in this volume include: · Advanced object-oriented programming techniques · Composition · Interfaces · Inheritance · Polymorphism · Operator overloading · Extension methods · Anonymous types · Custom type formatting · Creational design patterns · Assemblies and libraries · File I/O · Program configurations · Serialization · Software reliability This book will reinforce your programming skills and provide key insights into the world of object-oriented programming. Additionally, the topics learned in this volume will prepare you for advanced C# techniques such as: multi-threaded programming, generics, reflection and using the DLR.