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Civil Engineering & Engineering Mechanics, understanding soil structures interaction analysis in time domain. Beneficial to building development, erosion, science studies of geology, biology and civil and mechanical engineering, etc.

One of the foundations of molecular biology is how the interactions of proteins with DNA control many aspects of gene expression. Since the mid-20th century discoveries of the lac repressor and operator and the competition between the cI and cro proteins for the same segment of DNA, we have learned an enormous amount about the interactions of proteins with DNA and their control of fundamental processes in the cell. Introduction to Protein-DNA Interactions: Structure, Thermodynamics, and Bioinformatics describes what we know about protein-DNA interactions from the complementary perspectives of molecular and structural biology and bioinformatics and how each perspective informs the others. A particular emphasis is on how insights from experimental work can be translated into specific computational approaches to create unified view of the field and a fuller understanding of protein-DNA interactions.

The study of the interactions of proteins, whether they be enzymes, regulatory proteins or structural proteins, with nucleic acids is one of the most exciting areas of modern molecular biology. In this 1993 text, Professor Steitz reviews the wide-ranging research in structural studies of DNA-binding proteins and their complexes with DNA. The author clearly and concisely describes the uses of techniques in molecular genetics, DNA synthesis, protein crystallography and nuclear magnetic response. The book, by a now Nobel Prize-winning author, will continue to be enjoyed by anyone with an interest in this exciting area of research.

This important publication addresses the interactions of proteins with nonspecific binding sites on DNA as they play critical roles in fundamental cellular processes such as transcription, DNA replication, and recombination. The book presents current reviews of the biochemistry of representative nonspecific DNA-protein systems, and of their physiological functions. It includes chapters on the techniques used to characterize the complexes, on their thermodynamic properties, and on the role of nonspecific binding as gene regulatory proteins search for specific target sites on the chromosome. Systems considered include the effects of nonspecific binding in regulation of the lactose operon of Escherichia coli, the T4 bacteriophage gene 32 protein, the E. coli single strand binding (SSB) protein and recA protein, eukaryotic SSB's and histone-DNA complexes. The book presents those proteins displaying multiple modes of DNA binding as participants in more than one cellular process. This monograph combines rigorous descriptions of new findings for these important systems with provocative interpretations of the biological significance of the results. It is of great value to researchers ranging from graduate students to senior scientists in the areas of biochemistry, microbiology and molecular/cell biology.

The Finite-Difference Time-domain (FDTD) method allows you to compute electromagnetic interaction for complex problem geometries with ease. The simplicity of the approach coupled with its far-reaching usefulness, create the powerful, popular method presented in The Finite Difference Time Domain Method for Electromagnetics. This volume offers timeless applications and formulations you can use to treat virtually any material type and geometry.The Finite Difference Time Domain Method for Electromagnetics explores the mathematical foundations of FDTD, including stability, outer radiation boundary conditions, and different coordinate systems. It covers derivations of FDTD for use with PEC, metal, lossy dielectrics, gyrotropic materials, and anisotropic materials. A number of applications are completely worked out with numerous figures to illustrate the results. It also includes a printed FORTRAN 77 version of the code that implements the technique in three dimensions for lossy dielectric materials. There are many methods for analyzing electromagnetic interactions for problem geometries. With The Finite Difference Time Domain Method for Electromagnetics, you will learn the simplest, most useful of these methods, from the basics through to the practical applications.

The Finite-Difference Time-domain (FDTD) method allows you to compute electromagnetic interaction for complex problem geometries with ease. The simplicity of the approach coupled with its far-reaching usefulness, create the powerful, popular method presented in The Finite Difference Time Domain Method for Electromagnetics. This volume offers timeless applications and formulations you can use to treat virtually any material type and geometry.The Finite Difference Time Domain Method for Electromagnetics explores the mathematical foundations of FDTD, including stability, outer radiation boundary conditions, and different coordinate systems. It covers derivations of FDTD for use with PEC, metal, lossy dielectrics, gyrotropic materials, and anisotropic materials. A number of applications are completely worked out with numerous figures to illustrate the results. It also includes a printed FORTRAN 77 version of the code that implements the technique in three dimensions for lossy dielectric materials. There are many methods for analyzing electromagnetic interactions for problem geometries. With The Finite Difference Time Domain Method for Electromagnetics, you will learn the simplest, most useful of these methods, from the basics through to the practical applications.

This book starts out by presenting the evidence for hydrophilic interactions in biochemical processes and then goes on to describe the applications of the hydrophilic interactions in these processes, specifically protein folding, protein association, self assembly and molecular recognition.In Part I of this series, it was shown that the role of the so-called hydrophobic effect in biochemical processes was over-exaggerated. On the other hand, both experimental data and theoretical arguments support the conclusion that the hydrophilic, rather than hydrophobic interactions are the more important effects. In this volume, the author focuses on the applications of the hydrophilic interactions in processes such as solubility of proteins, protein folding, self assembly and molecular recognition. Hydrophilic interactions provide a powerful and coherent explanation of some biochemical processes, which until recently, were not understood.There are no other books of this kind. There are two books which deal with the role of hydrophobic effects (by C Tanford and A Ben-Naim), but these are quite obsolete.

This book starts out by presenting the evidence for hydrophilic interactions in biochemical processes and then goes on to describe the applications of the hydrophilic interactions in these processes, specifically protein folding, protein association, self assembly and molecular recognition.In Part I of this series, it was shown that the role of the so-called hydrophobic effect in biochemical processes was over-exaggerated. On the other hand, both experimental data and theoretical arguments support the conclusion that the hydrophilic, rather than hydrophobic interactions are the more important effects. In this volume, the author focuses on the applications of the hydrophilic interactions in processes such as solubility of proteins, protein folding, self assembly and molecular recognition. Hydrophilic interactions provide a powerful and coherent explanation of some biochemical processes, which until recently, were not understood.There are no other books of this kind. There are two books which deal with the role of hydrophobic effects (by C Tanford and A Ben-Naim), but these are quite obsolete.

This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells.Expert researchers introduce the most advanced technologies and techniques in protein structure and foldingIncludes techniques on tiling assays

Impairments in social functioning are among the hallmark characteristics of schizophrenia. These deficits predict relapse rate and may be independent of better-studied symptoms such as hallucinations. Additionally, studies indicate that social functioning is one of the most important domains for individuals with schizophrenia, many of whom consider social functioning to be a key area of unmet need.Social Cognition and Interaction Training (SCIT) is a group psychotherapy for individuals with schizophrenia and other psychotic disorders. Social cognition refers to the thinking processes that people use to navigate the social world. Deficits in social cognition hinder people with schizophrenia and other mental illnesses from living meaningful, socially connected lives. The SCIT Clinician Guide provides comprehensive instruction for mental health professionals to enhance social cognition and promote rewarding social lives for their clients. SCIT is appropriate for adults suffering from psychotic illness and who have interpersonal difficulties as a result. SCIT is particularly appropriate for individuals with symptoms of suspiciousness and paranoia. The authors summarize the rationale and theoretical underpinnings of SCIT, distinguish it from other treatments for psychosis, provide an overview of the intervention, explain the links between the intervention activities and the underlying theoretical model, and describe SCIT implementation session-by-session. SCIT is a 20- to 24-week group-based treatment that can be delivered by mental health clinicians of all levels in a wide range of community and hospital settings. SCIT uses exercises, games, discussion formats, and interactive social stimuli to target and improve specific areas of social cognitive dysfunction, and includes user-friendly tips and handouts for clients. It also provides web access to a library of videos, images and slide shows that are used to bring the SCIT training sessions to life.

This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells.Expert researchers introduce the most advanced technologies and techniques in protein structure and foldingIncludes techniques on tiling assays

P>Of related interest . . . THE COLLOIDAL DOMAIN Second Edition Where Physics, Chemistry, Biology, and Technology Meet D. Fennell Evans and Håkan Wennerström Fully updated and revised, this new edition of the critically acclaimed book incorporates information on key developments in colloid science and technology in the twentieth century. It provides a unified treatment of colloid theory, methods, and applications to specific systems, complete with concept maps, new worked examples, and more than 250 illustrations. 1999 (0-471-24247-0) 672 pp. FUNDAMENTALS OF INTERFACIAL ENGINEERING Robert J. Stokes and D. Fennell Evans This book emphasizes the importance of the intermolecular forces that hold materials together within a bulk phase or across an interface. It examines the fundamentals of the intermolecular interactions along with the properties, processing, and behavior of fluid interfacial systems. Solid surfaces and interfaces are also discussed. 1996 (0-471-18647-3) 736 pp. POLYMER HANDBOOK Fourth Edition Edited by J. Brandrup, E. H. Immergut, and E. A. Grulke Now in a fourth edition, the Polymer Handbook is one of the most comprehensive resources of fundamental, validated property data of polymeric materials necessary for polymer research. This edition boasts over 30% new material, covering such advances as the new pvt relationships and copolymer reactivity parameters. Improved nomenclature for better indexing and search and retrieval is also provided. 1999 (0-471-16628-6) 2336 pp.

This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells.Expert researchers introduce the most advanced technologies and techniques in protein structure and foldingIncludes techniques on tiling assays

P>Of related interest . . . THE COLLOIDAL DOMAIN Second Edition Where Physics, Chemistry, Biology, and Technology Meet D. Fennell Evans and Håkan Wennerström Fully updated and revised, this new edition of the critically acclaimed book incorporates information on key developments in colloid science and technology in the twentieth century. It provides a unified treatment of colloid theory, methods, and applications to specific systems, complete with concept maps, new worked examples, and more than 250 illustrations. 1999 (0-471-24247-0) 672 pp. FUNDAMENTALS OF INTERFACIAL ENGINEERING Robert J. Stokes and D. Fennell Evans This book emphasizes the importance of the intermolecular forces that hold materials together within a bulk phase or across an interface. It examines the fundamentals of the intermolecular interactions along with the properties, processing, and behavior of fluid interfacial systems. Solid surfaces and interfaces are also discussed. 1996 (0-471-18647-3) 736 pp. POLYMER HANDBOOK Fourth Edition Edited by J. Brandrup, E. H. Immergut, and E. A. Grulke Now in a fourth edition, the Polymer Handbook is one of the most comprehensive resources of fundamental, validated property data of polymeric materials necessary for polymer research. This edition boasts over 30% new material, covering such advances as the new pvt relationships and copolymer reactivity parameters. Improved nomenclature for better indexing and search and retrieval is also provided. 1999 (0-471-16628-6) 2336 pp.

Talk in Action examines the language, identity, and interaction of social institutions, introducing students to the research methodology of Conversation Analysis. Features a unique focus on real-world applications of CA by examining four institutional domains: calls to emergency numbers, doctor-patient interaction, courtroom trials, and mass communication, Provides a theoretical and methodological overview of the roots of CA, reviewing the main developments and findings of research on talk and social institutions conducted over the past 25 years Showcases the significance of this subject to everyday events, making it ideal for students coming to the field for the first time Written by two leading figures in the field of Conversation Analysis

This MIE volume provides laboratory techniques that aim to predict the structure of a protein which can have tremendous implications ranging from drug design, to cellular pathways and their dynamics, to viral entry into cells.Expert researchers introduce the most advanced technologies and techniques in protein structure and foldingIncludes techniques on tiling assays

Casebook of Neuropsychiatry is comprised of 38 clinical cases based on real patient interactions that straddle the domains of neurology and psychiatry. While scientifically rigorous and grounded in neuroanatomy and neurochemistry, the cases are written in an accessible, down-to-earth style that makes them easy to relate to and understand. The book is designed to supplement comprehensive texts (such as Yudofsky's American Psychiatric Publishing Textbook of Neuropsychiatry and Behavioral Neuroscience, Fifth Edition) by providing real-world accounts of patient presentations - such as dopamine excess in a Parkinson's patient or post-stroke depression - that clinicians are likely to encounter. The book focuses on skills that are not typically emphasized in general psychiatric or neurological training, filling a critical gap and broadening the reader's knowledge base. The book takes the clinical presentation as the starting point, using a specific case to describe the approach, the differential diagnosis, the diagnostic workup, the neuroanatomical and neurochemical basis of psychopathology, and contemporary treatment options. By demonstrating how experienced neuropsychiatrists grapple with diagnostic dilemmas and treatment approaches, Casebook of Neuropsychiatry brings the subspecialty alive in a unique and compelling way.

This volume explores the nature of interactions between the East and the West in the field of medicine. It brings into focus conditions and historical processes through which there was an interaction between the social and medical domains, particularly under the rubric of colonialism. It discusses India's medical tradition and the challenges it faced when modern medical system entered the country; the exchange of knowledge between India and the west; and the influence of local medicinal knowledge on its colonial counterpart. The exchange of ideas and that of tradition was not a simple journey but rather a long and tortuous trajectory which was characterized by both assimilation as well as initiative which sought to differentiate one set of ideas from another. The level of interaction was seldom smooth and it was often ridden with the languages of dominance and hegemony. Through specific examples and case studies, the book also analyses various ailments and the changing medical domain from the point of view of the existing social norms/conditions.

Clifford algebras are assuming now an increasing role in theoretical physics. Some of them predominantly larger ones are used in elementary particle theory, especially for a unification of the fundamental interactions. The smaller ones are promoted in more classical domains. This book is intended to demonstrate usefulness of Clifford algebras in classical electrodynamics. Written with a pedagogical aim, it begins with an introductory chapter devoted to multivectors and Clifford algebra for the three-dimensional space. In a later chapter modifications are presented necessary for higher dimension and for the pseudoeuclidean metric of the Minkowski space. Among other advantages one is worth mentioning: Due to a bivectorial description of the magnetic field a notion of force surfaces naturally emerges, which reveals an intimate link between the magnetic field and the electric currents as its sources. Because of the elementary level of presentation, this book can be treated as an introductory course to electromagnetic theory. Numerous illustrations are helpful in visualizing the exposition. Furthermore, each chapter ends with a list of problems which amplify or further illustrate the fundamental arguments.

Designed to help students explore interactions in both personal and professional domains, and develop the specific skills necessary to creating and maintaining healthy relationships, Inter-Act: Interpersonal Communication Concepts, Skills, and Contexts, Fourteenth Edition, retains the features that have made this book so successful: a theory driven and skills-based focus, an accessible tone and presentation, and a multitude of useful pedagogical tools. For this edition, new coauthor Erina MacGeorge has brought her in-depth knowledge of current theory to bear on each chapter, thoroughly updating the material so that it reflects the current state of knowledge in the discipline. Lively and well-written, Inter-Act features numerous activities that enable students to relate their everyday experiences to their studies in communication. It also addresses readers' experiences of communicating across differences in individual identity, gender, and culture. With a strong focus on the importance of ethics, this leading text encourages students to develop their analytic abilities as they think critically about key concepts in interpersonal communication.