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A valuable reference for repairing soft-tissue defectsReturning in a second edition, this book is a beautifully illustrated guide to facial soft-tissue reconstruction, written by leading clinicians who share insights into the most effective techniques for managing a range of problems in this area of surgery. It opens with a review of soft-tissue biomechanics and physiology and then covers the fundamentals of wound closure, wound healing, grafts, flaps, and dermabrasion. The chapters that follow address defects in specific anatomic regions. Each chapter presents a brief overview of the anatomy of the region and then goes on to provide succinct descriptions of surgical approaches for the relevant subunits in that region. New in this edition is a final chapter that provides detailed discussion of the latest graft harvesting techniques.Features of the second edition:Algorithms that guide the clinician through treatment options and to the selection of the appropriate flap or graft for each situationMore than 300 high-quality illustrations, full-color clinical photographs, and diagrams precisely depicting key surgical conceptsUp-to-date coverage of the newest flaps in facial reconstructive surgeryThis book is ideal for clinicians and residents in otolaryngology-head and neck surgery, facial plastic and reconstructive surgery, oral and maxillofacial surgery, and trauma management. It will also be a useful reference for dermatologists and ophthalmologists.

2019 EP release. K-pop boy band GOT7 launches its second subunit composed of two members. The new subunit, Jus2, consists of JB and Yugyeom. JB previously paired with another member, Jinyoung, to form a pop duo, JJ Project, under GOT7. JJ Project last released an album in mid-2018, titled Verse 2.

How do business enterprises control their subunits? In what ways do existing paths of communication within a firm affect its ability to absorb new technology and techniques? How do American banks affect how companies operate? Do theoretical constructs correspond to actual behavior? Because business enterprises are complex institutions, these questions can prove difficult to address. All too often, firms are treated as the atoms of economics, the irreducible unit of analysis. This accessible volume, suitable for course use, looks more closely at the American firm—into its internal workings and its genesis in the Gilded Age. Focusing on the crucial role of imperfect and asymmetric information in the operation of enterprises, Inside the Business Enterprise forges an innovative link between modern economic theory and recent business history.

The new edition of Bruce Wingerd's The Human Body: Concepts of Anatomy and Physiology helps encourage learning through concept building, and is truly written with the student in mind. Learning Concepts divide each chapter into easily absorbed subunits of information, making learning more achievable. Since students in a one-semester course may have little experience with biological and chemical concepts, giving them tools such as "concept statements," "concept check" questions, and a "concept block study sheet" at the end of each chapter help them relate complex ideas to simple everyday events. The book also has a companion Student Notebook and Study Guide (available separately) that reinvents the traditional study guide by giving students a tool to help grasp information in class and then reinforce learning outside of class. With additional, powerful options like the ADAM Interactive Anatomy Online Student Lab Activity Guide, students have access to learning activities to help them study, understand, and retain critical course information.

The new edition of Bruce Wingerd's The Human Body: Concepts of Anatomy and Physiology helps encourage learning through concept building, and is truly written with the student in mind. Learning Concepts divide each chapter into easily absorbed subunits of information, making learning more achievable. Since students in a one-semester course may have little experience with biological and chemical concepts, giving them tools such as "concept statements," "concept check" questions, and a "concept block study sheet" at the end of each chapter help them relate complex ideas to simple everyday events. The book also has a companion Student Notebook and Study Guide (available separately) that reinvents the traditional study guide by giving students a tool to help grasp information in class and then reinforce learning outside of class. With additional, powerful options like the ADAM Interactive Anatomy Online Student Lab Activity Guide, students have access to learning activities to help them study, understand, and retain critical course information.

Within subunits of a democratic federation, lasting political practices that restrict choice, limit debate, and exclude or distort democratic participation have been analyzed in recent scholarship as subnational authoritarianism. Once a critical number of citizens or regions band together in these practices, they can leverage illiberal efforts at the federal level. This timely, data-driven book compares federations that underwent transitions in the first, second, and third waves of democratization and offers a substantial expansion of the concept of subnational authoritarianism. The eleven expert political scientists featured in this text examine the nature and scope of subnational democratic variations within six large federations, including the United States, India, Mexico, Brazil, Argentina, and Russia. Illiberal Practices makes the case that subnational units are more likely to operate by means of illiberal structures and practices than as fully authoritarian regimes. Detailed case studies examine uneven levels of citizenship in each federal system. These are distributed unequally across the different regions of the country and display semi-democratic or hybrid characteristics. Appropriate for scholars and students of democratization, authoritarianism, federalism, decentralization, and comparative politics, Illiberal Practices sheds light on the uneven extension of democracy within countries that have already democratized.Contributors: Jacqueline Behrend, André Borges, Julián Durazo Herrmann, Carlos Gervasoni, Edward L. Gibson, Desmond King, Inga A.-L. Saikkonen, Celina Souza, Maya Tudor, Laurence Whitehead, Adam Ziegfeld

Bridging the gap between quantitative and qualitative approaches, this book presents methods for interrelating and integrating the variables, findings, and evaluations from the facets of the case (i.e., different perspectives of inquiry such as participant observation, open-ended interviews, etc.) or subunits of case inquiry. Using case examples from five different disciplines (neuropsychology, education, law, business, and environmental sciences), the authors show the reader how to use the embedded case design to enhance synthesis and knowledge integration. The authors share their broad knowledge of the philosophy of science to explain the rationale behind each step of embedded case designs, and recap each explanation with concept recaps called "lessons to be learned." In addition, they include a variety of boxes that offer statistical models for doing the analysis. This book offers readers a sophisticated approach to integrating mixed methods in case studies.  

The Third Edition examines United States First Amendment law using expertly edited cases, original note materials, and class questions. The Third Edition includes, among other things:New units or subunits on statutory protections for cyberspace speech (47 U.S.C. 230) and liability for distributing others' false statements; Coverage of important new First Amendment cases dealing with campaign finance, expressive association, expressive conduct, compelled speech, student speech in K-12 schools, government endorsement of religion, discrimination in favor of religious exemption requests, and the Religious Freedom Restoration Act.

In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s.

Within subunits of a democratic federation, lasting political practices that restrict choice, limit debate, and exclude or distort democratic participation have been analyzed in recent scholarship as subnational authoritarianism. Once a critical number of citizens or regions band together in these practices, they can leverage illiberal efforts at the federal level. This timely, data-driven book compares federations that underwent transitions in the first, second, and third waves of democratization and offers a substantial expansion of the concept of subnational authoritarianism. The eleven expert political scientists featured in this text examine the nature and scope of subnational democratic variations within six large federations, including the United States, India, Mexico, Brazil, Argentina, and Russia. Illiberal Practices makes the case that subnational units are more likely to operate by means of illiberal structures and practices than as fully authoritarian regimes. Detailed case studies examine uneven levels of citizenship in each federal system. These are distributed unequally across the different regions of the country and display semi-democratic or hybrid characteristics. Appropriate for scholars and students of democratization, authoritarianism, federalism, decentralization, and comparative politics, Illiberal Practices sheds light on the uneven extension of democracy within countries that have already democratized.Contributors: Jacqueline Behrend, André Borges, Julián Durazo Herrmann, Carlos Gervasoni, Edward L. Gibson, Desmond King, Inga A.-L. Saikkonen, Celina Souza, Maya Tudor, Laurence Whitehead, Adam Ziegfeld

Drawing the Map of Life takes the story of the Human Genome Project from its origins, through the race to its accomplishment, and on to today's vast efforts to exploit the complete, ordered sequence of the 3 billion subunits of DNA, the molecule of heredity. It is the first account to deal in depth and balance with the intellectual roots of the project, the motivations that drove it, and the hype that often masked genuine triumphs. McElheny profiles key people, such as David Botstein, Eric Lander, Francis Collins, Watson, Michael Hunkapiller and Craig Venter. He also shows that, besides being a major event in the history of science, one that is revolutionizing medicine, the Human Genome Project is a striking example of how new techniques and instruments (such as restriction enzymes and sequencing methods), often arriving first, shape the type of questions scientists then ask.

In the early 1990s, almost 200 yr after Edward Jenner demonstrated the effectiveness of the smallpox vaccine, a new paradigm for vaccination emerged. The conventional method of vaccination required delivery of whole pathogens or structural subunits, but in this new approach, DNA or genetic information was administered to elicit an immunological response. Once it was observed that plasmid DNA delivered in vivo led to production of an encoded transgene (1), two ground-breaking studies demonstrated that immunological responses could be generated against antigenic transgenes via plasmid DNA delivered by DNA vaccination (as this approach is called) (2,3). The appe- ance of this new vaccination strategy coincided with advances in molecular biology, which provided new tools to study and manipulate the basic elements of an organism’s genome and also could also be applied to the design and production of DNA vaccines. DNA Vaccines is a major updated and enhancement of the first edition. It reviews state-of-the-art methods in DNA vaccine technology, with chapters describing DNA vaccine design, delivery systems, adjuvants, current appli- tions, methods of production, and quality control. Consistent with the approach of the Methods in Molecular Medicine series, these chapters contain detailed practical procedures on the latest DNA vaccine technology. The enthusiasm for DNA vaccine technology is made clear by the number of research studies published on this topic since the mid-1990s.