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In recent years, the emphasis in drug development has been the design of new delivery systems rather than new drugs. It is the aim of innovative pharmaceutical scientists to design the new dosage forms to overcome the body's barrier mechanisms which have specifically evolved to exclude foreign material.This book provides an integrated approach to the study of drug formulation in the body with the emphasis on the formulation variables rather than the drugs. The link between physiology and pharmaceutics is presented to give an essential background of biological principles for the pharmacy student, pharmaceutical formulator and healthcare professional. Complex mathematical aspects of physical chemistry have been avoided to facilitate understanding, enabling the reader to concentrate on how the biological environment affects the performance of the drugs and dosage forms. As the majority of drugs are administered via the oral route a large proportion of the book is devoted to the gastrointestinal tract and the variation in the capacity for drug absorption which occurs along its length. Transdermal, ocular, pulmonary and nasal drug delivery are discussed in detail. New chapters in the book include 'Vaginal drug delivery', the 'Blood brain barrier' and 'Parenteral drug delivery'.

The life and work of the groundbreaking interior designer and inventor of the "California Look."One of the most innovative, imitated, and internationally respected design icons of the twentieth century, Michael Taylor brought with him a new vision that changed California's, and the profession's, approach to interiors. More than fifty of his commissions and other projects, ranging from classical to "Californian," illustrate the breadth of his talent. 300 color photographs

The life and work of the groundbreaking interior designer and inventor of the "California Look."One of the most innovative, imitated, and internationally respected design icons of the twentieth century, Michael Taylor brought with him a new vision that changed California's, and the profession's, approach to interiors. More than fifty of his commissions and other projects, ranging from classical to "Californian," illustrate the breadth of his talent. 300 color photographs

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Francis Bacon: A Retrospective by Dennis; Bacon, Francis; Yard, Sally; Peppiatt, Michael; Yale Center for Br Farr.

The historiography of English Catholicism has grown enormously in the last generation, led by scholars such as Peter Lake, Michael Questier, Stefania Tutino, and others. In Suspicious Moderate, Anne Ashley Davenport makes a significant contribution to that literature by presenting a long overdue intellectual biography of the influential English Catholic theologian Francis à Sancta Clara (1598–1680). Born into a Protestant family in Coventry at the end of the sixteenth century, Sancta Clara joined the Franciscan order in 1617. He played key roles in reviving the English Franciscan province and in the efforts that were sponsored by Charles I to reunite the Church of England with Rome. In his voluminous Latin writings, he defended moderate Anglican doctrines, championed the separation of church and state, and called for state protection of freedom of conscience. Suspicious Moderate offers the first detailed analysis of Sancta Clara's works. In addition to his notorious Deus, natura, gratia (1634), Sancta Clara wrote a comprehensive defense of episcopacy (1640), a monumental treatise on ecumenical councils (1649), and a treatise on natural philosophy and miracles (1662). By carefully examining the context of Sancta Clara's ideas, Davenport argues that he aimed at educating English Roman Catholics into a depoliticized and capacious Catholicism suited to personal moral reasoning in a pluralistic world. In the course of her research, Davenport also discovered that "Philip Scot," the author of the earliest English discussions of Hobbes (a treatise published in 1650), was none other than Sancta Clara. Davenport demonstrates how Sancta Clara joined the effort to fight Hobbes's Erastianism by carefully reflecting on Hobbes's pioneering ideas and by attempting to find common ground with him, no matter how slight.

In June of 1963, when Michael Peppiatt first met Francis Bacon, the former was a college boy at Cambridge, the latter already a famous painter, more than thirty years his senior. And yet, Peppiatt was welcomed into the volatile artist's world; Bacon, considered by many to be "mad, bad, and dangerous to know," proved himself a devoted friend and father figure, even amidst the drinking and gambling. Though Peppiatt would later write perhaps the definitive biography of Bacon, his sharply drawn memoir has a different vigor, revealing the artist at his most intimate and indiscreet, and his London and Paris milieus in all their seediness and splendor. Bacon is felt with immediacy, as Peppiatt draws from contemporary diaries and records of their time together, giving us the story of a friendship, and a new perspective on an artist of enduring fascination.

"Francis: The Journey and the Dream depicted a Francis who 'sang' to me. I felt that I had found a teacher to lead me home. I had no idea where this was going to lead, but I was ready to follow."—John Michael Talbot One of the most influential saints' books, with over 200,000 copies sold, Francis: The Journey and the Dream continues to inspire people of all ages with its lyrical prose and depth of love for the Poor Man of Assisi. This beautiful anniversary edition includes Fr. Bodo's story of writing the book and its worldwide influence, a reader's guide for book clubs and discussion groups, and a list of Fr. Bodo's favorite Franciscan resources, culled over three decades of research on Francis and his followers.The audio edition of this book can be downloaded via Audible.

"Francis: The Journey and the Dream depicted a Francis who 'sang' to me. I felt that I had found a teacher to lead me home. I had no idea where this was going to lead, but I was ready to follow."—John Michael Talbot One of the most influential saints' books, with over 200,000 copies sold, Francis: The Journey and the Dream continues to inspire people of all ages with its lyrical prose and depth of love for the Poor Man of Assisi. This beautiful anniversary edition includes Fr. Bodo's story of writing the book and its worldwide influence, a reader's guide for book clubs and discussion groups, and a list of Fr. Bodo's favorite Franciscan resources, culled over three decades of research on Francis and his followers.The audio edition of this book can be downloaded via Audible.

The life of St. Francis of Assisi was a paradigm of simplicity, humanity, and love. In today's busy world, his practices have enormous appeal, described in this inspiring work by John Michael Talbot, the founder of The Brothers and Sisters of Charity, a lay order based on the Franciscan principles of simplicity and self-sufficiency. In The Lessons Of St. Francis, Talbot and co-author Steve Rabey demonstrate the enduring significance of Franciscan wisdom. Organized by topic, such as Simplicity, Humility, Compassion, Solitude, Service, and Prayer, each chapter includes excerpts from the writings of St. Francis, as well as those of his followers and biographers. Combining deep spiritual insights with the offer of a saner, less chaotic way of living, The Lessons Of St. Francis offers wise advice on how to incorporate these virtues into our own lives today.

The historiography of English Catholicism has grown enormously in the last generation, led by scholars such as Peter Lake, Michael Questier, Stefania Tutino, and others. In Suspicious Moderate, Anne Ashley Davenport makes a significant contribution to that literature by presenting a long overdue intellectual biography of the influential English Catholic theologian Francis à Sancta Clara (1598–1680). Born into a Protestant family in Coventry at the end of the sixteenth century, Sancta Clara joined the Franciscan order in 1617. He played key roles in reviving the English Franciscan province and in the efforts that were sponsored by Charles I to reunite the Church of England with Rome. In his voluminous Latin writings, he defended moderate Anglican doctrines, championed the separation of church and state, and called for state protection of freedom of conscience. Suspicious Moderate offers the first detailed analysis of Sancta Clara's works. In addition to his notorious Deus, natura, gratia (1634), Sancta Clara wrote a comprehensive defense of episcopacy (1640), a monumental treatise on ecumenical councils (1649), and a treatise on natural philosophy and miracles (1662). By carefully examining the context of Sancta Clara's ideas, Davenport argues that he aimed at educating English Roman Catholics into a depoliticized and capacious Catholicism suited to personal moral reasoning in a pluralistic world. In the course of her research, Davenport also discovered that "Philip Scot," the author of the earliest English discussions of Hobbes (a treatise published in 1650), was none other than Sancta Clara. Davenport demonstrates how Sancta Clara joined the effort to fight Hobbes's Erastianism by carefully reflecting on Hobbes's pioneering ideas and by attempting to find common ground with him, no matter how slight.

This instrument is part of our fifth annual Contemporary American Makers Exhibition, 2022 Michael is currently the Shop Foreman of Francis Morris ...

Hickey, Michael M., Traywick, Ben T., Taylor, Paul R.

Night Work: the second book in David C. Taylor's transporting historical crime fiction series.Michael Cassidy, a New York cop plagued by dreams that sometimes come true, escorts a prisoner accused of murder to Havana on the cusp of Fidel Castro's successful revolution against the Batista dictatorship. After delivering the man to La Cabaña prison and rescuing Dylan McCue, a Russian KGB agent and his now-married former lover, from her scheduled execution, Cassidy returns to New York and retreats into the comforts of alcohol and sex.The arrival of Fidel Castro in New York three months later complicates the cop's life once more. Cassidy's investigation of a young man's murder in Central Park is interrupted when he is assigned to Castro's protective detail. Castro has many enemies. American mobsters who have been run out of Havana, businessmen who worry about their investments in Cuba, and members of Batista's secret police all want him dead. Cassidy is already investigating one murder. Can he prevent another?

*A 2016 Mystery Writers of America Edgar Award Nominee for Best Novel*Winner of the 2016 Nero Wolfe Award for Best American MysteryDavid C. Taylor's Night Life takes us back to New York City in 1954.The Cold War is heating up. Senator Joe McCarthy is running a witch hunt for Communists in America. The newly formed CIA is fighting a turf battle with the FBI to see who will be the primary US intelligence agency. And the bodies of murdered young men are turning up in the city.Michael Cassidy has an unusual background for a New York cop. His father, a refugee from Eastern Europe, is a successful Broadway producer. His godfather is Frank Costello, a Mafia boss. Cassidy also has an unusual way of going about the business of being a cop-maybe that's why he threw a fellow officer out a third story window of the Cortland Hotel.Cassidy is assigned to the case of Alexander Ingram, a Broadway chorus dancer found tortured and dead in his apartment in Hell's Kitchen. Complications grow as other young men are murdered one after the other. And why are the FBI, the CIA, and the Mafia interested in the death of a Broadway gypsy?Meanwhile, a mysterious, beautiful woman moves into Cassidy's building in Greenwich Village. Is Dylan McCue a lover or an enemy? Cassidy is plagued by nightmares-dreams that sometimes become reality. And he has been dreaming that someone is coming to kill him.

The Art of Michael Parkes II will feature the artist’s new works, including drawings, paintings, and sculptures, and showcases many of Parkes’ well-known pieces. Parkes’ art is internationally acclaimed as the best of the “imaginary realism” or “magical realism” art genre. Art historian John Russell Taylor’s introduction explains Parkes’ mastery and place in art history. The indexed collection in this new book shows the beginning of Parkes’ career until the present, illuminating Parkes’ artistic development in painting, sculpture, drawing, and stone lithography. Over 65 new or unpublished images are included with many photographs of Parkes at work in Switzerland, Italy, Spain, and India. Two completely new sections have been added. The new sculpture section shows more sculpture than any previous Parkes book. Close-up photographs of the bronzes enable us to see their beauty with incredible detail. The new drawing section includes older drawings never seen before and recent drawings through 2008.

The Art of Michael Parkes II will feature the artist’s new works, including drawings, paintings, and sculptures, and showcases many of Parkes’ well-known pieces. Parkes’ art is internationally acclaimed as the best of the “imaginary realism” or “magical realism” art genre. Art historian John Russell Taylor’s introduction explains Parkes’ mastery and place in art history. The indexed collection in this new book shows the beginning of Parkes’ career until the present, illuminating Parkes’ artistic development in painting, sculpture, drawing, and stone lithography. Over 65 new or unpublished images are included with many photographs of Parkes at work in Switzerland, Italy, Spain, and India. Two completely new sections have been added. The new sculpture section shows more sculpture than any previous Parkes book. Close-up photographs of the bronzes enable us to see their beauty with incredible detail. The new drawing section includes older drawings never seen before and recent drawings through 2008.

In the pages of this book, Francis Costello allows Michael Collins to speak in his own words. He traces Collins's career from his school days to his tragic death at the age of 31, through a series of edited extracts from Collins's writings, speeches, letters and memoranda. Using a chronological narrative, Costello provides linking text to set the context for each extract from Collins. He draws his material from sources as diverse as printed books, the Collins papers in the National Library of Ireland, the Military History Bureau of the Department of Defence, Dail Reports, contemporary newspaper accounts and the private papers of many who came into contact with Collins. The Michael Collins revealed in these pages is a complex, multi-faced man: politician; head of intelligence; Minister for Finance; friend and lover. Getting behind the myth, this book shows us the real Collins - in his own words.