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The incidence of Lyme disease has increased in the last 20 years and threatens to increase more in the future. Lyme disease can be hard to detect and can have serious consequences if not treated. This issue covers both acute and chronic Lyme disease, with detailed descriptions of the various body systems affected, and also discusses diagnosis and treatment.

Back in 1987, Peter Rand was a Maine Medical Center doctor with a penchant for research and a love for the Maine coast. These led him to tackle the puzzle of Lyme disease, which had been first described only a decade earlier in Connecticut. As more and more people in New England were coming down with Lyme, it became imperative to understand the parasitic insects that spread it: the deer tick. As his first laboratory, Rand chose Monhegan Island. Monhegan is famous for massive headlands and an old-growth spruce forest, and is a destination for bird enthusiasts and generations of artists. It is also the year-round home of fishermen who maintain a way of life that has been the essence of the island for five centuries. But the island was also perfect for a project to understand the life cycle of deer ticks and then, perhaps, to learn how to control them. Isolated twelve miles from the mainland, Monhegan had an overabundant population of deer, introduced in 1954, yet none of the mice that scientists thought were essential to the tick life cycle. How do deer ticks get to an island, and how do they survive without a crucial host? Of Ticks and Islands is Pete Rand’s charming account of doing science on the islands of Maine. One part scientific detective story, one part love letter to Maine island life, Rand’s memoir describes a decade of tick-related work that he and others did on Monhegan, Matinicus, and Isle au Haut that ultimately led to deeper understanding of deer ticks in Maine and the eventual elimination of Lyme disease on Monhegan following the complete removal of deer. People who love Maine’s coast and islands and those who love narratives of scientific minds at work will love Of Ticks and Islands.

Back in 1987, Peter Rand was a Maine Medical Center doctor with a penchant for research and a love for the Maine coast. These led him to tackle the puzzle of Lyme disease, which had been first described only a decade earlier in Connecticut. As more and more people in New England were coming down with Lyme, it became imperative to understand the parasitic insects that spread it: the deer tick. As his first laboratory, Rand chose Monhegan Island. Monhegan is famous for massive headlands and an old-growth spruce forest, and is a destination for bird enthusiasts and generations of artists. It is also the year-round home of fishermen who maintain a way of life that has been the essence of the island for five centuries. But the island was also perfect for a project to understand the life cycle of deer ticks and then, perhaps, to learn how to control them. Isolated twelve miles from the mainland, Monhegan had an overabundant population of deer, introduced in 1954, yet none of the mice that scientists thought were essential to the tick life cycle. How do deer ticks get to an island, and how do they survive without a crucial host? Of Ticks and Islands is Pete Rand’s charming account of doing science on the islands of Maine. One part scientific detective story, one part love letter to Maine island life, Rand’s memoir describes a decade of tick-related work that he and others did on Monhegan, Matinicus, and Isle au Haut that ultimately led to deeper understanding of deer ticks in Maine and the eventual elimination of Lyme disease on Monhegan following the complete removal of deer. People who love Maine’s coast and islands and those who love narratives of scientific minds at work will love Of Ticks and Islands.

Biology of Ticks is the most comprehensive work on tick biology and tick-borne diseases. This second edition is a multi-authored work, featuring the research and analyses of renowned experts across the globe. Spanning two volumes, the book examines the systematics, biology, structure, ecological adaptations, evolution, genomics and the molecular processes that underpin the growth, development and survival of these important disease-transmitting parasites. Also discussed is the remarkable array of diseases transmitted (or caused) by ticks, as well as modern methods for their control. This book should serve as a modern reference for students, scientists, physicians, veterinarians and other specialists. Volume I covers the biology of the tick and features chapters on tick systematics, tick life cycles, external and internal anatomy, and others dedicated to specific organ systems, specifically, the tick integument, mouthparts and digestive system, salivary glands, waste removal, salivary glands, respiratory system, circulatory system and hemolymph, fat body, the nervous and sensory systems and reproductive systems. Volume II includes chapters on the ecology of non-nidicolous and nidicolous ticks, genetics and genomics (including the genome of the Lyme disease vector Ixodes scapularis) and immunity, including host immune responses to tick feeding and tick-host interactions, as well as the tick's innate immune system that prevents and/or controls microbial infections. Six chapters cover in depth the many diseases caused by the major tick-borne pathogens, including tick-borne protozoa, viruses, rickettsiae of all types, other types of bacteria (e.g., the Lyme disease agent) and diseases related to tick paralytic agents and toxins. The remaining chapters are devoted to tick control using vaccines, acaricides, repellents, biocontrol, and, finally, techniques for breeding ticks in order to develop tick colonies for scientific study.

Biology of Ticks is the most comprehensive work on tick biology and tick-borne diseases. This second edition is a multi-authored work, featuring the research and analyses of renowned experts across the globe. Spanning two volumes, the book examines the systematics, biology, structure, ecological adaptations, evolution, genomics and the molecular processes that underpin the growth, development and survival of these important disease-transmitting parasites. Also discussed is the remarkable array of diseases transmitted (or caused) by ticks, as well as modern methods for their control. This book should serve as a modern reference for students, scientists, physicians, veterinarians and other specialists. Volume I covers the biology of the tick and features chapters on tick systematics, tick life cycles, external and internal anatomy, and others dedicated to specific organ systems, specifically, the tick integument, mouthparts and digestive system, salivary glands, waste removal, salivary glands, respiratory system, circulatory system and hemolymph, fat body, the nervous and sensory systems and reproductive systems. Volume II includes chapters on the ecology of non-nidicolous and nidicolous ticks, genetics and genomics (including the genome of the Lyme disease vector Ixodes scapularis) and immunity, including host immune responses to tick feeding and tick-host interactions, as well as the tick's innate immune system that prevents and/or controls microbial infections. Six chapters cover in depth the many diseases caused by the major tick-borne pathogens, including tick-borne protozoa, viruses, rickettsiae of all types, other types of bacteria (e.g., the Lyme disease agent) and diseases related to tick paralytic agents and toxins. The remaining chapters are devoted to tick control using vaccines, acaricides, repellents, biocontrol, and, finally, techniques for breeding ticks in order to develop tick colonies for scientific study.

With millions around the world infected—and millions more at risk—Lyme and tick-related diseases are now today's fastest growing infectious diseases. Yet, even as the number of Lyme disease sufferers continues to climb and other dangerous tick-borne disorders emerge, diagnosis remains elusive, often hampering chances of early treatment. Now, this complete guide tells you everything you need to know to protect yourself and your family from the pain of Lyme disease, including expert advice on: Recognizing the symptoms of Lyme disease Finding the best medical treatment Avoiding disease-carrying ticks Accessing online information on vaccines, repellents, and the latest research Finding self-help and support organizations, state medical complaint boards, products, and related services

Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online.In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade’s advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.

Guest editor Rosalie Trevejo highlights important areas in veterinary public health for all small animal practitioners. Topics include emerging tick-borne diseases, animal bites and rabies risk, influenza, animals as sentinels, antibiotic resistance, feral cat populations, border health, the human-animal bond, zoonotic diseases, disaster preparedness, reporting of animal diseases, and much more!

In these pages, you will find updated information on central nervous system infections, skin and soft tissue infections, community-acquired pneumonia, tick-borne diseases, urinary tract infections, Mycobacterium tuberculosis and nontuberculous mycobacterial infections, sexually transmitted infections, bioterrorism, travel medicine, infectious gastrointestinal syndromes, transplant-associated infections, HIV and AIDS, health care-associated infections, and other clinical challenges, including 108 all-new peer-reviewed, psychometrically validated, multiple-choice questions (MCQs) for self-assessment and study. MKSAP (R) 18 is specifically intended for physicians who provide personal, non-surgical care to adults, including general internists and primary care physicians, subspecialists who need to remain up-to-date in internal medicine, residents preparing for the Certification Exam in internal medicine, physicians preparing for the Maintenance of the Certification Exam in internal medicine, and medical educators. The learning objectives of MKSAP (R) 18 are: - Close gaps between actual care in your practice and preferred standards of care, based on best evidence. - Diagnose disease states that are less common and sometimes overlooked or confusing. - Improve management of comorbid conditions that can complicate patient care. - Determine when to refer patients for surgery or care by subspecialists. - Pass the ABIM Certification Examination and the ABIM Maintenance of Certification Examination.

A single tick bite can have debilitating consequences. Lyme disease is the most common disease carried by ticks in the United States, and the number of those afflicted is growing steadily. If left untreated, the diseases carried by ticks--known as tick-borne diseases--can cause severe pain, fatigue, neurological problems, and other serious health problems. The Institute of Medicine held a workshop October 11-12, 2010, to examine the state of the science in Lyme disease and other tick-borne diseases. Table of ContentsFront MatterOverview1 Introduction2 An Overview of Tick-Borne Diseases3 The Social Construction and Human Face of Tick-Borne Disease4 Emerging Infections, Tick Biology, and Host-Vector Interactions5 Surveillance, Spectrum, and Burden of Tick-Borne Disease, and At-Risk Populations6 Pathogenesis7 Diagnostics and Diagnosis8 Prevention9 Closing PanelsReferencesAppendix A: Commissioned PapersAppendix B: Federal Funding of Tick-Borne DiseasesAppendix C: Summary of Public Comment on AgendaAppendix D: Workshop AgendaAppendix E: Public Comment SummaryAppendix F; Speaker Biosketches

The Lyme Disease Solution is a comprehensive guide to the diagnosis and treatment of Lyme disease and other tick borne infections. The author, Dr. Kenneth Singleton, is a board certified specialist in Internal Medicine who himself struggled with severe symptoms of Lyme disease for 8 years prior to being correctly diagnosed and treated. His book is full of medical wisdom and practical pearls of clinical information that every Lyme patient will find immensely useful. Though detailed, the book is easy to read and comprehend. Dr. Singleton does a masterful job of breaking down very complex medical information into simple and easily understandable concepts. The insightfulness and thoroughness of the many topics covered by Dr. Singleton testify to his deep understanding of and passion for patients afflicted with Lyme disease. This book is a "must have" for all chronic Lyme (and other tick borne illness) patients and for their families. This is not an autographed book. All sales are final.

Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online.In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade’s advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.

Lyme disease is the most common tick-borne illness in the United States, with more than 300,000 cases diagnosed each year. However, doctors are deeply divided on how to diagnose and treat it, giving rise to the controversy known as the “Lyme Wars.” Firmly entrenched camps have emerged, causing physicians, patient communities, and insurance providers to be pitted against one another in a struggle to define Lyme disease and its clinical challenges. Health care providers may not be aware of its diverse manifestations or the limitations of diagnostic tests. Meanwhile, patients have felt dismissed by their doctors and confused by the conflicting opinions and dubious self-help information found online.In this authoritative book, the Columbia University Medical Center physicians Brian A. Fallon and Jennifer Sotsky explain that, despite the vexing “Lyme Wars,” there is cause for both doctors and patients to be optimistic. The past decade’s advances in precision medicine and biotechnology are reshaping our understanding of Lyme disease and accelerating the discovery of new tools to diagnose and treat it, such that the great divide previously separating medical communities is now being bridged. Drawing on both extensive clinical experience and cutting-edge research, Fallon, Sotsky, and their colleagues present these paradigm-shifting breakthroughs in language accessible to both sides. They clearly explain the immunologic, infectious, and neurologic basis of chronic symptoms, the cognitive and psychological impact of the disease, as well as current and emerging diagnostic tests, treatments, and prevention strategies. Written for the educated patient and health care provider seeking to learn more, Conquering Lyme Disease gives an up-to-the-minute overview of the science that is transforming the way we address this complex illness. It argues forcefully that the expanding plague of Lyme and other tick-borne diseases can be confronted successfully and may soon even be reversed.

I grew up on a farm in a small town in Minnesota. I left the farm for New York with training in medicine and epidemiology.I opened a practice in an area highly endemic for Lyme disease in 1987. It has become a hot topic. I have shared my understanding of the science of Lyme and related tick-borne illness with my colleagues as president of a medical society, as author of evidence-based guidelines, and as a clinical epidemiologist. My colleagues have criticized me. I keep writing and speaking up.I have faith that a better understanding of the science of tick-borne illnesses will help my patients.