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In the heart of a geological upthrust, four presidents, memorialized in granite, gaze across the rugged country of South Dakota’s Black Hills. At the foot of the mountain lies Keystone, a small community indelibly linked to the carving of Mount Rushmore. In 1876, prospectors swarmed into the central Black Hills in search of gold. While they did find it, these early miners also found other minerals, such as tin and feldspar. By the turn of the 20th century, Keystone was well-known for its mineral riches, but also for the boom and bust cycles that often accompany mining. The town’s future was guaranteed in 1925, however, when Gutzon Borglum, a noted sculptor, arrived to secure a location for a monument to American democracy. Borglum drew heavily on the skills of Keystone miners, putting them to work on a mountain that would soon portray the images of Presidents Washington, Jefferson, Lincoln, and Roosevelt. In this book, readers will find vintage photographs―many never before published―that, along with engaging narrative, tell the story of Keystone and the carving of Mount Rushmore.

This item is printed on demand - it takes 3-4 days longer - Neuware -The design and fabrication of aptamer-based biosensors for point-of-care testing of disease diagnostic and prognostic is an upthrust and interdisciplinary area of research. This book covers the design and development of novel cost-effective aptamer-based biosensors for disease diagnostic and prognostic including an understanding of health care management in terms of timely updates of disease situations in a particular geographical area. It also discusses the scaling up and market trend of aptamer-based devices for extension of research from lab to market, and end users.Features:Explains the design and fabrication of aptasensors-based diagnostic devicesIncludes novel approaches and comprehensive technology overview for diagnosis management towards early-stage detection of various biomarkers associated with several health conditionsDemonstrates possible benefits of combined diagnostics and therapeutic possibilities using aptamer-based point-of-care technologies devicesDiscusses emerging implications and recent advances of biosensing platforms for designing and developing aptamer-based point-of-care testing (POCT) devicesExplores aptamer-based approach to develop advanced platforms for medical applications and open arena for state-of-the-art future researchThis book is aimed at researchers and graduate students in biomedical engineering, diagnostics, nanobiotechnology, and materials science. 298 pp. Englisch