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Thoroughly revised and updated for its Sixth Edition, Dubois' Lupus Erythematosus remains the definitive reference on this disease. More than sixty distinguished authorities provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus--including definition, classification, epidemiology, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition's clinically oriented chapters include timely information on the new classification for lupus, undifferentiated connective tissue disease, biologic therapies, cox-2 interventions, clinical trial methodologies, and outcomes research. Completely rewritten basic science sections reflect recent findings on genetics, inflammatory mediator biology, cytokine physiology, cell signaling, and newly described animal models and autoantibodies.A Brandon-Hill recommended title.

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For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

...a comprehensive study of every aspect of lupus, the exte nsive clinical section from previous editons has been retain ed while the basic science section has been expanded.

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Thoroughly revised and updated for its Sixth Edition, Dubois' Lupus Erythematosus remains the definitive reference on this disease. More than sixty distinguished authorities provide comprehensive coverage of every aspect of cutaneous and systemic lupus erythematosus--including definition, classification, epidemiology, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education. This edition's clinically oriented chapters include timely information on the new classification for lupus, undifferentiated connective tissue disease, biologic therapies, cox-2 interventions, clinical trial methodologies, and outcomes research. Completely rewritten basic science sections reflect recent findings on genetics, inflammatory mediator biology, cytokine physiology, cell signaling, and newly described animal models and autoantibodies.A Brandon-Hill recommended title.

...a comprehensive study of every aspect of lupus, the exte nsive clinical section from previous editons has been retain ed while the basic science section has been expanded.

For more than 50 years, Dubois’ Lupus Erythematosus and Related Syndromes has been recognized internationally as the go-to clinical reference on lupus and other connective tissue diseases. From basic scientific principles to practical points of clinical management, the updated 9th Edition provides extensive, authoritative coverage of systemic lupus erythematosus (SLE) and its related diseases in a logical, clearly written, user-friendly manner. It’s an ideal resource for rheumatologists and internal medicine practitioners who need a comprehensive clinical reference on all aspects of SLE, connective tissue diseases, and the antiphospholipid syndromes.Provides complete clinical coverage of every aspect of cutaneous and systemic lupus erythematosus, including definitions, pathogenesis, autoantibodies, clinical and laboratory features, management, prognosis, and patient education.Contains an up-to-date overview of significant advances in cellular, molecular, and genetic technologies, including genetic advancements in identifying at-risk patients.Offers an increased focus on the clinical management of related disorders such as Sjogren’s syndrome, scleroderma, polymyositis, and antiphospholipid syndrome (APS).Presents the knowledge and expertise of more international contributors to provide new global perspectives on manifestations, diagnosis, and treatment.Features a vibrant, full-color format, with graphs, algorithms, differential diagnosis comparisons, and more schematic diagrams throughout.Expert Consult™ eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, and references from the book on a variety of devices.

Systemic lupus erythematosus is an autoimmune disease that can affect any system and organ in the body. For the 1.4 million people in the United States who have lupus, an overactive immune system senses that different parts of the body do not belong, and it attacks these parts. The immune system may strike the cells that line the joints or tendons, for example, causing pain and swelling. An incredibly complex disease, lupus must be properly treated for the optimal health and well-being of the person who has it. The Lupus Encyclopedia is an authoritative compendium that provides detailed explanations of every body system potentially affected by the disease, along with practical advice about coping. People with lupus, their loved ones, caregivers, and medical professionals―all will find here an invaluable resource. Illustrated with photographs, diagrams, and tables, The Lupus Encyclopedia explains symptoms, diagnostic methods, medications and their potential side effects, and when to seek medical attention. Dr. Donald Thomas provides information for women who wish to become pregnant and advises readers about working with a disability, complementary and alternative medicine, infections, cancer, and a host of other topics.

Arthritis is usually considered a disease of older adults, but nearly 300,000 children in the United States suffer from some form of arthritis or rheumatic disease, such as juvenile arthritis (JRA), fibromyalgia, chronic fatigue, systemic lupus erythematosus, scleroderma, or Kawasaki disease. Yet until now very little information has been available to guide parents and doctors in properly diagnosing such children. Here is a readable, reliable guide to the common causes of bone, joint, muscle, and arthritis pain in children, designed to help parents and physicians understand these disorders, arrive at the proper diagnosis, and choose the most effective treatment. In this comprehensive resource, Dr. Thomas Lehman--the head of one of the most prestigious pediatric rheumatology programs in the world--offers easy-to-understand information on the causes, symptoms, tests, and treatments for a wide variety of rheumatic diseases and childhood pain. Dr. Lehman writes with great clarity, providing numerous case examples that illustrate the topic at hand and offering practical, down-to-earth advice. Equally important, he answers the questions that parents are most likely to ask: What should they observe in their children? What questions should they ask their doctor? Which tests are necessary? What risk factors should they be aware of? And how can they help their children cope with the social and psychological aspects of their illness. The book summarizes diagnostic tests, discusses the most effective medications, and discusses physical therapy, alternative therapy, and surgical options that are available. Clearly written, thorough, authoritative, and up-to-date, It's Not Just Growing Pains is the definitive resource available on the subject for parents and health care professionals, helping them to understand the children's pain and find the best available care.

Systemic lupus erythematosus is an autoimmune disease that can affect any system and organ in the body. For the 1.4 million people in the United States who have lupus, an overactive immune system senses that different parts of the body do not belong, and it attacks these parts. The immune system may strike the cells that line the joints or tendons, for example, causing pain and swelling. An incredibly complex disease, lupus must be properly treated for the optimal health and well-being of the person who has it. The Lupus Encyclopedia is an authoritative compendium that provides detailed explanations of every body system potentially affected by the disease, along with practical advice about coping. People with lupus, their loved ones, caregivers, and medical professionals―all will find here an invaluable resource. Illustrated with photographs, diagrams, and tables, The Lupus Encyclopedia explains symptoms, diagnostic methods, medications and their potential side effects, and when to seek medical attention. Dr. Donald Thomas provides information for women who wish to become pregnant and advises readers about working with a disability, complementary and alternative medicine, infections, cancer, and a host of other topics.

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases.

Lichen Planus is a rare, mucocutaneous, disorder involving an itchy rash, lesions or papules -- areas of inflamed eruptions – that recurs over a period of months or years. Special forms of lichen planus include: Drug-induced lichen planus, Lupus erythematosus-lichen planus overlap syndrome, Lichen planus pemphigoide, Keratosis lichenoides chronica, Lichenoid reaction of graft-versus-host disease, Lichenoid keratosis and Lichenoid dermatits. If you or a loved one has lichen planus, this invaluable reference contains causes, tests and available treatments along with a complete reference guide.

From the inside cover: When Henrietta Aladjem experienced her first symptoms of systemic lupus erythematosus in 1953, she did not know that the dizziness, headaches, and nausea were only the beginning of a grueling, fifteen-year battle with a mysterious disease. ....

This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases.

From the inside cover: When Henrietta Aladjem experienced her first symptoms of systemic lupus erythematosus in 1953, she did not know that the dizziness, headaches, and nausea were only the beginning of a grueling, fifteen-year battle with a mysterious disease. ....

Lichen Planus is a rare, mucocutaneous, disorder involving an itchy rash, lesions or papules -- areas of inflamed eruptions – that recurs over a period of months or years. Special forms of lichen planus include: Drug-induced lichen planus, Lupus erythematosus-lichen planus overlap syndrome, Lichen planus pemphigoide, Keratosis lichenoides chronica, Lichenoid reaction of graft-versus-host disease, Lichenoid keratosis and Lichenoid dermatits. If you or a loved one has lichen planus, this invaluable reference contains causes, tests and available treatments along with a complete reference guide.