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The Fever Trail is a fascinating trip through the history of Malaria and those that have sought to cure it. The book starts with the hunt for the Cinchono tree, the tree that yielded the cure for Malaria, quinine. The trio of explorers given the task of transporting the tree to the colonies gave most of their lives so that the world could be free of intermittent fevers. They never though that the disease would mutate. The modern pioneers no longer search out forests, or spend months on dangerous rivers. Instead they battle on in laboratories and facilities desperate to find what has eluded mankind for centuries. A cure.

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A clear, concise discourse of 300 years of malarial drug research. Presents a historical overview of antimalarial medicines and examines future challenges in the discovery and development of effective treatments and control strategies. Provides new perspectives on the creative process of drug discovery and the challenges of overcoming drug resistance. Discusses the use of larvicides, bednets, and DDT as well as recombinant DNA and monoclonal antibodies to block malaria transmission from mosquitoes to humans. Serves as a resource for microbiologists, parasitologists, pharmacologists, medicinal chemists, biochemists, physicians, and drug researchers.

Known for his signature growl and a vigorously melodic flow, South Bronx native known as Nine ignited the music scene at a time when hip hop's birthplace lacked solid representation. Soon after his arrival, he tore a huge hole into rap's status quo by ushering in a hardcore vibe that catered directly to the urban landscape and paved the way for the maelstrom of rugged mc's that subsequently followed. With "that voice" that packs an effortless punch over jagged beats and deft picturesque rhymes c

About the brand: Finely-crafted home furnishings with a unique flair. Color/finish: natural/grey oil-based paint Design details: Keep your home tidy and organized at all times with the convenience of the Quinine laundry basket. Featuring a bamboo butterfly frame and a grey fabric basket, the laundry basket remains both stylish and handy. Its removable laundry bag includes handles, allowing you to easily haul clothes from room to room. The roomy laundry basket can double up as a hamper to increase the organization and efficiency of your laundry room, bedroom, or bath. Measurements: 15.4in x 15.4in x 27.6in Assembly required Bamboo, Linen Although leather is one of the most durable upholstery materials, proper care is vital to maintain its appearance and performance. Dust weekly using a soft, clean cloth slightly dampened with distilled water. Blot spills immediately with a soft, clean absorbent dry cloth. Imported

Tonic water elicits images of sparkling drinks and stirred concoctions, but it has a history that reaches beyond the bar. Its roots go back centuries, starting with the Andes and the cinchona tree, and it had its start as a natural medicine instead of as a tasty mixer. Quinine, tonic water’s signature ingredient, was once used to treat Malaria and is still used by some to soothe leg cramps. From the Quechua people and Spanish colonists, to French chemists and British officers, the journey from botanical discovery to cocktail staple is a fascinating story.Just the Tonic is an accessible yet informative history of tonic water, written by leading experts from the Royal Botanic Gardens, Kew—which is home to one of the largest collections in the world of historic cinchona. It takes us through the discovery and development of quinine and its eventual meeting with sparkling water. It also introduces us to the basic botany and development of the cinchona tree. The iconic gin and tonic cocktail is not forgotten in these pages. The authors look at the changing role of the drink, tracing the rise and fall, and rise again, of cocktails straight from officers’ messes of British India, the art deco cocktail bars of the 1920s, through to the Mad Men era and the recent resurgence of gin as a drink of choice. A final chapter on cocktail recipes provides instructions on how to make delicious alcoholic and nonalcoholic drinks using an array of different tonics and spirits. Mixed into the book are reproductions of stunning historical artwork, posters, and photographs. This is the first authoritative book on the history and role of tonic water, making it the perfect addition to both bookshelves and bar carts.

In the eighteenth century, malaria was a prevalent and deadly disease, and the only effective treatment was found in the Andean forests of Spanish America: a medicinal bark harvested from cinchona trees that would later give rise to the antimalarial drug quinine. In 1751, the Spanish Crown asserted control over the production and distribution of this medicament by establishing a royal reserve of “fever trees” in Quito. Through this pilot project, the Crown pursued a new vision of imperialism informed by science and invigorated through commerce. But ultimately this project failed, much like the broader imperial reforms that it represented. Drawing on extensive archival research, Matthew Crawford explains why, showing how indigenous healers, laborers, merchants, colonial officials, and creole elites contested European science and thwarted imperial reform by asserting their authority to speak for the natural world. The Andean Wonder Drug uses the story of cinchona bark to demonstrate how the imperial politics of knowledge in the Spanish Atlantic ultimately undermined efforts to transform European science into a tool of empire.

In the manner of Barbara Tuchman and Paul Johnson, a superior, popular account of how five plants--quinine, sugar, tea, cotton and the potato--have determined the course of history. Illustrated.

Excerpt from Travels in Peru and India While Superintending the Collection of Chinchona Plants and Seeds in South America, and Their Introduction Into IndiaThe introduction of quinine-yielding Chinchona-trees into India, and the cultivation of the Peruvian Bark in our Eastern possessions, where that inesti mable febrifuge is almost a necessary of life, has for some years engaged the attention of the Indian Government. In 1859 the author of the present work was intrusted, by the Secretary of State for India in Council, with the duty of superintending all the necessary arrangements for the collection of Chin chona-plants and seeds of the species esteemed in commerce, in South America, and for their introduc tion into India. This important measure has now been crowned with complete success, and it is the object of the following pages to relate the previous history of the Chinchona-plant; to describe the forests in South America where the most valuable species grow; to record the labours of those who were engaged in exploring them; and to give an account of all the proceedings connected with the cultivation of Chinchona-plants in India.About the PublisherForgotten Books publishes hundreds of thousands of rare and classic books. Find more at www.forgottenbooks.comThis book is a reproduction of an important historical work. Forgotten Books uses state-of-the-art technology to digitally reconstruct the work, preserving the original format whilst repairing imperfections present in the aged copy. In rare cases, an imperfection in the original, such as a blemish or missing page, may be replicated in our edition. We do, however, repair the vast majority of imperfections successfully; any imperfections that remain are intentionally left to preserve the state of such historical works.