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Ceftriaxone for injection, USP is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration. Ceftriaxone sodium is (6R, 7R)-7-[2-(2-Amino-4-thiazolyl) glyoxylamido]-8-oxo-3-[[(1, 2, 5, 6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 72-(Z)-(O-methyloxime), disodium salt, sesquaterhydrate. Ceftriaxone is a third-generation of cephalosporins which is used for community acquired infections such as pneumonia and urinaly tract infections. It showed great advantage of once-daily administration based on pharmacological manner and need no renal impairment. It is stable for β-lactamases against first- or second- generations of cephalosporins. Ceftriaxone is also used for streptococcal endocarditis as alternative first-line therapeutic regimen and used for Sexually Transmited Disease (STD) such as syphilis and chancoroid.

Ceftriaxone for injection, USP is a sterile, semisynthetic, broad-spectrum cephalosporin antibiotic for intravenous or intramuscular administration. Ceftriaxone sodium is (6R, 7R)-7-[2-(2-Amino-4-thiazolyl) glyoxylamido]-8-oxo-3-[[(1, 2, 5, 6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio]methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 72-(Z)-(O-methyloxime), disodium salt, sesquaterhydrate. Ceftriaxone is a third-generation of cephalosporins which is used for community acquired infections such as pneumonia and urinaly tract infections. It showed great advantage of once-daily administration based on pharmacological manner and need no renal impairment. It is stable for β-lactamases against first- or second- generations of cephalosporins. Ceftriaxone is also used for streptococcal endocarditis as alternative first-line therapeutic regimen and used for Sexually Transmited Disease (STD) such as syphilis and chancoroid.

This new edition of Jean BrunetonFs book has been revised and expanded with over 200 additional pages reflecting the most recent advances in natural and semisynthetic substances. It also features the most recen t additions to the therapeutic arsenal such as antimalarial, ntitumor and antiretroviral agents.