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This book aims to provide the reader with a working knowledge of the various means of controlling the solubility or dissolution rate of a drug or other solute in an aqueous medium. The book begins with the factors which govern solubility in general and then looks at aqueous solubility in particular, including the properties of liquid mixtures and the thermodynamics of solutions formed from mixing two components. The bulk of the book is then devoted to techniques for altering solubility and dissolution rate of organic compounds in aqueous media. It discusses in detail the most commonly used solubility enhancers: buffers, cosolvents, surfactants, and complexants. Each chapter is self-contained and emphasizes the details for applying the techniques.

This book aims to provide the reader with a working knowledge of the various means of controlling the solubility or dissolution rate of a drug or other solute in an aqueous medium. The book begins with the factors which govern solubility in general and then looks at aqueous solubility in particular, including the properties of liquid mixtures and the thermodynamics of solutions formed from mixing two components. The bulk of the book is then devoted to techniques for altering solubility and dissolution rate of organic compounds in aqueous media. It discusses in detail the most commonly used solubility enhancers: buffers, cosolvents, surfactants, and complexants. Each chapter is self-contained and emphasizes the details for applying the techniques.

866 Seiten Das hier angebotene Buch stammt aus einer teilaufgelösten Bibliothek und kann die entsprechenden Kennzeichnungen aufweisen (Rückenschild, Instituts-Stempel.); der Buchzustand ist ansonsten ordentlich und dem Alter entsprechend gut. Original-Schutzumschlag vorhanden (siehe Foto). In ENGLISCHER Sprache. Sprache: Englisch Gewicht in Gramm: 1380

This item is printed on demand. 2.1800

Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including polymers, inorganic salts, and biological materials. To update his groundbreaking handbook with the latest advances and perspectives, Charles M. Hansen has invited five renowned experts to share their work, theories, and practical applications involving HSPs. New discussions include a new statistical thermodynamics approach for confirming existing HSPs and how they fit into other thermodynamic theories for polymer solutions. Entirely new chapters examine the prediction of environmental stress cracking as well as absorption and diffusion in polymers. Highlighting recent findings on interactions with DNA, the treatment of biological materials also includes skin tissue, proteins, natural fibers, and cholesterol. The book also covers the latest applications of HSPs, such as ozone-safe “designer” solvents, protective clothing, drug delivery systems, and petroleum applications. Presenting a comprehensive survey of the theoretical and practical aspects of HSPs, Hansen Solubility Parameters, Second Edition concludes with a detailed discussion on the necessary research, future directions, and potential applications for which HSPs can provide a useful means of prediction in areas such as biological materials, controlled release applications, nanotechnology, and self-assembly.

Hansen solubility parameters (HSPs) are used to predict molecular affinities, solubility, and solubility-related phenomena. Revised and updated throughout, Hansen Solubility Parameters: A User's Handbook, Second Edition features the three Hansen solubility parameters for over 1200 chemicals and correlations for over 400 materials including polymers, inorganic salts, and biological materials. To update his groundbreaking handbook with the latest advances and perspectives, Charles M. Hansen has invited five renowned experts to share their work, theories, and practical applications involving HSPs. New discussions include a new statistical thermodynamics approach for confirming existing HSPs and how they fit into other thermodynamic theories for polymer solutions. Entirely new chapters examine the prediction of environmental stress cracking as well as absorption and diffusion in polymers. Highlighting recent findings on interactions with DNA, the treatment of biological materials also includes skin tissue, proteins, natural fibers, and cholesterol. The book also covers the latest applications of HSPs, such as ozone-safe “designer” solvents, protective clothing, drug delivery systems, and petroleum applications. Presenting a comprehensive survey of the theoretical and practical aspects of HSPs, Hansen Solubility Parameters, Second Edition concludes with a detailed discussion on the necessary research, future directions, and potential applications for which HSPs can provide a useful means of prediction in areas such as biological materials, controlled release applications, nanotechnology, and self-assembly.

Charles Hansen began his work with solvents in 1962, and almost immediately began producing new and groundbreaking results. Since then, his Hansen Solubility Parameters have been extensively used and proven valuable to a variety of industries, including coatings, adhesives, plastics, protective clothing, and environmental protection. They allow correlations and systematic comparisons previously not possible, such as polymer solubility, swelling and permeation, surface wetting and dewetting, the solubility of organic salts, and many biological applications. Until now, however, their seemingly universal ability to predict molecular affinities has been generally taken as semiempirical.Moving beyond the Hildebrand and Flory theories, Hansen found that his approach not only quantitatively describes hydrogen bonding and polar bonding in many types of systems, but in fact agrees with and extends the very general Prigogine theory. This explains why the correlations all seem to fit with an apparently "universal" 4: it results from the validity of applying the geometric mean rule to describe dispersion, permanent dipole-permanent dipole, and hydrogen bonding interaction in mixtures of unlike molecules. Hansen Solubility Parameters provides new tables of previously unpublished correlations and parameters. The author illuminates his text with practical examples related to coatings, biological systems, pigments, and fibers, and takes a general approach that makes this reference ideal for predicting compatibility, adsorption on surfaces, orientation toward materials of similar affinities (self-assembly), and other phenomena associated with solubility and affinity. Chemists, chemical engineers, and biochemists will find this book-the collected work and experience of the father of its concept-intriguing for its theory and invaluable for its data.

Former library book; may include library markings. Used book that is in clean, average condition without any missing pages.

Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, Solubility, Dissolution, and Charged State of Ionizable Molecules: Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars. Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules.

Firmness and lusterDissolves quickly and is easy to drinkImproved solubility! Improved solubility!Compared to our conventional productApproximately 25 kcal per servingContains 12 ingredientsEasy to dissolve! Easy to drink! Perfect powderLow molecular collagen 5300mg Hyaluronic acid 30mg Dietary fiber 1000mg Vitamin C 100mgCoQ10/Glucosamine/Elastin/4 kinds of herb mix (Dokudami, Hawthorn, Roman Chamomile, Grape leaf)Beauty constitution LactobacillusFor a full and resilient lifeAdd to coffee, cocoa, soups, yogurt, etc.Hot or iced!Easy to drink and keeps its delicious taste!How to use:One serving is 1 level spoon (7.4g) or 1 and 1/3 level tablespoons (7.4g) provided with the can. Take once or twice a day by dissolving it in your favorite drink or food. Drink promptly after dissolving.. Ingredient: Collagen peptide (gelatin), indigestible dextrin, reduced maltose, lactic acid bacteria powder (sterilized), vegetable oil, coenzyme Q10, porcine elastin peptide, mixed herb extract powder (dextrin, Houttuynia cordata, hawthorn, Roman chamomile, grape leaves), V. C, hyaluronic acid, flavoring, emulsifier, glucosamine (derived from shrimp and crab), sweetener (acesulfame K, sucralose) Energy per serving (7.4g): 25kcal Protein: 5.3g Fat/ 0.01 0.06g Sugar 0.50g Dietary fiber 1.0g Sodium 17 47mg Vitamin C 100mg CoQ10 1.0mg Glucosamine 10mg Per serving) Collagen...5300mg Hyaluronic acid...30mg Lactic acid bacteria powder (sterilized)...30mg Elastin...1mg

EasyPaks Neutral Cleaner features a concentrated, powdered compound that quickly dissolves in water to produce a cleaning dilution that can be varied to meet your needs. Cleaner combines the advantages of pre-measured with water-solubility for quick, simple use. Effervescing action ensures that both the cleaner and the packet will dissolve, quickly and completely. Phosphate-free formula leaves no dulling film, even without rinsing. Cleaner is perfect for surfaces ranging from terrazzo, marble, slate and vinyl to asphalt, ceramic tile, quarry tile, terrazzo, marble, concrete, painted surfaces and vinyl.

MILES PROPTECH GAS contains premium polyalkylene glycol (PAG) base fluids. and is specifically designed for use in propane gas compressor applications. MILES PROPTECH GAS is an ideal lubricant for these natural refrigerants due to its very low pour point, high viscosity index, excellent solubility and superior resistance against viscosity dilution.

With this comprehensive classroom supplement, students learn to focus on the scientific method and developing hypotheses. Topics covered include metric measurements, lab techniques, solubility, volume and density, radioactive decay, electrical circuits, and more! Making hydrogen gas and balloon rockets, and measuring a water droplet’s splatter size are just a few of the variety of experiments included!Mark Twain Media Publishing Company specializes in providing captivating, supplemental books and decorative resources to complement middle- and upper-grade classrooms. Designed by leading educators, the product line covers a range of subjects including mathematics, sciences, language arts, social studies, history, government, fine arts, and character. Mark Twain Media also provides innovative classroom solutions for bulletin boards and interactive whiteboards. Since 1977, Mark Twain Media has remained a reliable source for a wide variety of engaging classroom resources.

Mumford puts forward a new theory of dispositions, showing how central their role in metaphysics and philosophy of science is. Much of our understanding of the physical and psychological world is expressed in terms of dispositional properties--from the spin of a sub-atomic particle to the solubility of sugar. Mumford discusses what it means to say that something has a property of this kind and how dispositions can possibly be real things in the world.

A rigorous, comprehensive introduction to soil chemistry, this text is aimed at students and researchers who are not soil chemists. The author describes soil minerals and organic matter in soils and the soil solution, and provides in-depth coverage of important chemical processes, including solubility reactions, oxidation-reduction phenomena, adsorption, and ion exchange. The three final chapters present detailed applications to soil-plant relationships, fertilizer reactions in soils, acidity, salinity, mineral weathering, and soil management. Over 200 problems at varying levels of difficulty are coordinated with the text, and an appendix on SI units summarizes their use in soil chemistry.

Galois theory is one of the most beautiful branches of mathematics. By synthesising the techniques of group theory and field theory it provides a complete answer to the problem of the solubility of polynomials by radicals: that is, the problem of determining when and how a polynomial equation can be solved by repeatedly extracting roots and using elementary algebraic operations. This textbook, based on lectures given over a period of years at Cambridge, is a detailed and thorough introduction to the subject. The work begins with an elementary discussion of groups, fields and vector spaces, and then leads the reader through such topics as rings, extension fields, ruler-and-compass constructions, to automorphisms and the Galois correspondence. By these means, the problem of the solubility of polynomials by radicals is answered; in particular it is shown that not every quintic equation can be solved by radicals. Throughout, Dr Garling presents the subject not as something closed, but as one with many applications. In the final chapters, he discusses further topics, such as transcendence and the calculation of Galois groups, which indicate that there are many questions still to be answered. The reader is assumed to have no previous knowledge of Galois theory. Some experience of modern algebra is helpful, so that the book is suitable for undergraduates in their second or final years. There are over 200 exercises which provide a stimulating challenge to the reader.

Mumford puts forward a new theory of dispositions, showing how central their role in metaphysics and philosophy of science is. Much of our understanding of the physical and psychological world is expressed in terms of dispositional properties--from the spin of a sub-atomic particle to the solubility of sugar. Mumford discusses what it means to say that something has a property of this kind and how dispositions can possibly be real things in the world.

The Properties of Solvents Yizhak Marcus Hebrew University of Jerusalem, Israel The Properties of Solvents contains extensively annotated tables of physical, chemical and related properties for over 250 solvents. Factual knowledge of solvent effects on solvation, solubility, chemical equilibria and reaction rate is important for theoretical and practical applications. This volume will enable chemists to choose solvents rationally, taking into account solvent properties and the expected results. The Properties of Solvents is a valuable source of information for all who are interested in the behaviour of solutions. These include solution, organic, analytical and physical chemists. Contents * Introduction * Solvent effects * Physical properties * Chemical properties * Applications The Wiley Series in Solution Chemistry fills the increasing need to present authoritative, comprehensive and fully up-to-date accounts of the many aspects of solution chemistry. Internationally recognized experts from research or teaching institutions in various countries are invited to contribute to the series.

Nanoparticles, products of nanotechnology, are of increasing interest to the pharmaceutical community. They can increase drug solubility, enhance bioavailability, allow tissue targeting, offer decreased side-effects, and improve therapeutic efficacy. Presenting the most pertinent and practical issues in the manufacturing and biological application of nanoparticles, this source presents state-of-the-art scientific contributions by seasoned authorities in the field.

The solubility of gases and liquids in liquids is of great importance in large areas of operations based on chemical concepts. Phenomena have appeared to be so varied that even experts have from time to time remarked on the difficulty of seeing a consistent pattern. Now for the first time the essential pattern of all known gas solubility data is set out in a graphic form for all to see. The continuous merging of the gas-liquid systems and the liquid-liquid systems is also illustrated. The pattern opens the way to rational predictions. The new data given for the lower alkanes and alkenes, the three methylamines, ammonia, bromomethane, and chloroethane, together with my previously reported data on hydrogen sulfide, dimethyl ether, chloromethane, and sulfur dioxide, have been obtained by a bubbler-manometer procedure which is fully described. Not only are these data of significance in many chemical processes, but they have also been vital to the development of the overall essential pattern covering all gases. The book is for chemists, chemical engineers, biotechnologists, certain physi­ cists, and teachers and students in these disciplines. It is a book for all those who are concerned with the use and inculcation of the fundamental, even rudimentary, principles of chemistry.