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Like almost every major scientific or medical breakthrough in history, the transdermal delivery of drugs started as only an idea - slowly moving its way from the drawing board to actual testing and eventually approval. Today, there are more than 20 companies involved in transdermal drug delivery. In addition, almost every large pharmaceutical firm has ongoing transdermal delivery programs. But in spite of this effort and after 15 years from the introduction of the Nitroglycerin patch, only six transdermal drugs exist in the marketplace.The practice has been hampered by the fact that most drugs, as well as many excipients used in the manufacture of transdermal patches, cause skin irritation or skin sensitization. Similar problems exist with the application of dermatologicals and cosmetics to skin, which in many cases are equally as severe as those encountered in transdermal delivery.Biochemical Modulation of Skin Reactions: Transdermals, Topicals, Cosmetics presents a series of chapters describing technologies and the practical application of biochemicals which might lead to the reduction or abrogation of these skin reaction. In addition, it addresses those areas of skin immunology and skin sciences that account for the processes that control irritant and allergic contact dermatitis and outlines the numerous cellular and molecular factors involved in the development of irritation and sensitization.Indeed, Biochemical Modulation of Skin Reactions helps serve as a catalyst for further research in the field, allowing for more drugs and cosmetics to be applied to the skin without adverse effects.Features

A digital copy of "*Biochemical Sensors: Mimicking Gustato" by Kiyoshi Toko. Download is immediately available upon purchase!

Hardcover. Shipping may be from multiple locations in the US or from the UK, depending on stock availability.

The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: Illustrations integrating many different features of the reactions and their interrelationships Tables listing the important system components and their function Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: “... highly recommended for every scientist and student working in biochemistry.” –Umwelt & Gesundheit 4/2012 (review in German language)

Author's affiliation is not cited. Instructional manual of biochemical tests for identifying bacteria in the laboratory. This edition has been updated to include new nomenclature resulting from the significant advancements in the study of microorganisms. Abundant references. For students and professionals. Previous edition: c1980. Wire-spiral binding.

Completely revised, updated, and enlarged, this second edition now contains a subchapter on biorecognition assays, plus a chapter on bioprocess control added by the new co-author Jun-ichi Horiuchi, who is one of the leading experts in the field. The central theme of the textbook remains the application of chemical engineering principles to biological processes in general, demonstrating how a chemical engineer would address and solve problems. To create a logical and clear structure, the book is divided into three parts. The first deals with the basic concepts and principles of chemical engineering and can be read by those students with no prior knowledge of chemical engineering. The second part focuses on process aspects, such as heat and mass transfer, bioreactors, and separation methods. Finally, the third section describes practical aspects, including medical device production, downstream operations, and fermenter engineering. More than 40 exemplary solved exercises facilitate understanding of the complex engineering background, while self-study is supported by the inclusion of over 80 exercises at the end of each chapter, which are supplemented by the corresponding solutions. An excellent, comprehensive introduction to the principles of biochemical engineering.

The pathways and networks underlying biological function Now in its second edition, Biochemical Pathways continues to garner praise from students, instructors, and researchers for its clear, full-color illustrations of the pathways and networks that determine biological function. Biochemical Pathways examines the biochemistry of bacteria, plants, and animals. It offers a quick overview of the metabolic sequences in biochemical pathways, the chemistry and enzymology of conversions, the regulation of turnover, the expression of genes, the immunological interactions, and the metabolic background of health disorders. A standard set of conventions is used in all illustrations, enabling readers to easily gather information and compare the key elements of different biochemical pathways. For both quick and in-depth understanding, the book uses a combination of: Illustrations integrating many different features of the reactions and their interrelationships Tables listing the important system components and their function Text supplementing and expanding on the illustrated facts In the second edition, the volume has been expanded by 50 percent. Text and figures have undergone a thorough revision and update, reflecting the tremendous progress in biochemical knowledge in recent years. A guide to the relevant biochemical databases facilitates access to the extensive documentation of scientific knowledge. Biochemical Pathways, Second Edition is recommended for all students and researchers in such fields as biochemistry, molecular biology, medicine, organic chemistry, and pharmacology. The book's illustrated pathways aids the reader in understanding the complex set of biochemical reactions that occur in biological systems. From the reviews: “... highly recommended for every scientist and student working in biochemistry.” –Umwelt & Gesundheit 4/2012 (review in German language)

In addition to updating each chapter and including a new discussion of the gaseous neuromodulators nitric oxide and carbon monoxide, the authors have dropped a formerly featured chapter on metabolism in the CNS and incorporated most of this material into a new chapter on the genetic basis of neurological and psychiatric diseases. With the almost bi-weekly discovery of genes that appear to be involved in diseases of the nervous system, this area has the potential for providing a revolutionary kind of therapy, and it has been accorded greater attention. This versatile text continues to be the first choice for basic neuropharmacology and neuroscience courses in medical schools and at the undergraduate level, pharmacy schools, graduate pharmacology programs, and residency programs in psychiatry and neurology.

All engineering disciplines have been developed from the basic sciences. Science gives us the information on the reasoning behind new product development, whereas engineering is the application of science to manufacture the product at the commercial level. Biological processes involve various biomolecules, which come from living sources. It is now possible to manipulate DNA to get the desired changes in biochemical processes. This book provides students the knowledge that will enable them to contribute in various professional fields, including bioprocess development, modeling and simulation, and environmental engineering. It includes the analysis of different upstream and downstream processes. The chapters are organized in broad engineering subdisciplines, such as mass and energy balances, reaction theory using both chemical and enzymatic reactions, microbial cell growth kinetics, transport phenomena, different control systems used in the fermentation industry, and case studies of some industrial fermentation processes. Each chapter begins with a fundamental explanation for general readers and ends with in-depth scientific details suitable for expert readers. The book also includes the solutions to about 100 problems.

This work provides comprehensive coverage of modern biochemical engineering, detailing the basic concepts underlying the behaviour of bioprocesses as well as advances in bioprocess and biochemical engineering science. It includes discussions of topics such as enzyme kinetics and biocatalysis, microbial growth and product formation, bioreactor design, transport in bioreactors, bioproduct recovery and bioprocess economics and design. A solutions manual is available to instructors only.

New Book. Shipped from UK. Established seller since 2000.

This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology, residents in psychiatry and neurology, and clinicians and scientists. Both authoritative and very readable, it has been thoroughly updated for each edition. In the Eighth Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics, the major problem of drug delivery to the brain, and the growing recognition of nicotinic receptors in the brain and their possible involvement in Alzheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of the illustrations.

Author's affiliation is not cited. Instructional manual of biochemical tests for identifying bacteria in the laboratory. This edition has been updated to include new nomenclature resulting from the significant advancements in the study of microorganisms. Abundant references. For students and professionals. Previous edition: c1980. Wire-spiral binding.

There is no such thing as an average person, we are all genetically and biologically unique. But when sperm meets egg, our characteristics are not locked in stone. This work argues that bad genes do not necessarily cause disease by themselves, and nutrition and environment can alter the outcome.

This classic text gives a uniquely lucid and lively view of neurotransmitters, their role in nervous system function, and their involvement in the mechanisms of psychiatric drug action. For three decades it has served as an essential guide for students of neuroscience and psychopharmacology, residents in psychiatry and neurology, and clinicians and scientists. Both authoritative and very readable, it has been thoroughly updated for each edition. In the Eighth Edition more space is devoted to clinical examples, subclasses of receptors that provide targets for new drugs, molecular genetics, the major problem of drug delivery to the brain, and the growing recognition of nicotinic receptors in the brain and their possible involvement in Alzheimer's and Parkinson's diseases. In addition, the book's format has been enlarged and a second color added to many of the illustrations.

Biochemical Pathways An Atlas of Biochemistry and Molecular Biology Edited by Gerhard Michal Modern biochemistry is a complex field, combining areas of cell biology, molecular biology, medicine, immunology, genetics-even neuroscience. Many of these disciplines converge in the dynamic arena of research dealing with metabolic processes and other mechanisms present at the cellular and molecular level. Biochemical Pathways offers a truly unique road map to modern biochemistry. In full and vivid color, it features detailed charts-each color-coded and accompanied by a brief explanation-of metabolic pathways and their relationship to regulation pathways. Important mechanisms of molecular biology are reviewed in the second part of the book. This encyclopedic compendium goes well beyond traditional biochemistry to cover some very specialized pathways and many aspects of regulation. The clear, systematic presentation includes: * Metabolic structures and reaction mechanisms * The intermediates and enzymes involved * Metabolic branching points * Transcription and translation * Signal transduction * Transport mechanisms * Blood coagulation, immunology, and the complement system Current, referenced, and easy-to-use, Biochemical Pathways is bound to become a classic in the field. It is a one-of-a-kind visual guide for researchers and scholars in all areas of the life sciences.

Like almost every major scientific or medical breakthrough in history, the transdermal delivery of drugs started as only an idea - slowly moving its way from the drawing board to actual testing and eventually approval. Today, there are more than 20 companies involved in transdermal drug delivery. In addition, almost every large pharmaceutical firm has ongoing transdermal delivery programs. But in spite of this effort and after 15 years from the introduction of the Nitroglycerin patch, only six transdermal drugs exist in the marketplace.The practice has been hampered by the fact that most drugs, as well as many excipients used in the manufacture of transdermal patches, cause skin irritation or skin sensitization. Similar problems exist with the application of dermatologicals and cosmetics to skin, which in many cases are equally as severe as those encountered in transdermal delivery.Biochemical Modulation of Skin Reactions: Transdermals, Topicals, Cosmetics presents a series of chapters describing technologies and the practical application of biochemicals which might lead to the reduction or abrogation of these skin reaction. In addition, it addresses those areas of skin immunology and skin sciences that account for the processes that control irritant and allergic contact dermatitis and outlines the numerous cellular and molecular factors involved in the development of irritation and sensitization.Indeed, Biochemical Modulation of Skin Reactions helps serve as a catalyst for further research in the field, allowing for more drugs and cosmetics to be applied to the skin without adverse effects.Features

Designed to supplement and complement any standard biochemistry text or lecture notes, this book helps provide a balanced picture of modern biochemistry by use of elementary mathematics in understanding properties and behavior of biological molecules. It provides a balanced picture of modern biochemistry by using elementary mathematics to explore the properties and behavior of biological molecules. The text discusses such topics as:* Aqueous Solutions and Acid-Base Chemistry * Chemistry of Biological Molecules * Bioenergetics * Enzymes * Spectrophotometry and Other Optical Methods * Isotopes in Biochemistry. Sample problems are solved completely in a step-by-step manner, and the answer to all practice problems are given at the end of the book. With Biochemical Calculations, 2nd Edition , students will gain confidence in their ability to handle mathematical problems, discovering that biochemistry is more than memorization of structures and pathways.

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